ICAM3 Antibody (PACO19803)
- SKU:
- PACO19803
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ICAM3 Antibody (PACO19803) |
抗体コード: | PACO19803 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human ICAM3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19803(ICAM3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO19803(ICAM3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. |
シノニム: | intercellular adhesion molecule 3 |
UniProt Protein Function: | ICAM3: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM3 is also a ligand for integrin alpha-D/beta-2. Belongs to the immunoglobulin superfamily. ICAM family. |
UniProt Protein Details: | Protein type:Cell adhesion; Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:integrin binding; protein binding; receptor binding Biological Process: cell adhesion; extracellular matrix organization and biogenesis; regulation of immune response; stimulatory C-type lectin receptor signaling pathway |
NCBI Summary: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016] |
UniProt Code: | P32942 |
NCBI GenInfo Identifier: | 206729872 |
NCBI Gene ID: | 3385 |
NCBI Accession: | P32942.2 |
UniProt Secondary Accession: | P32942,Q6PD68, |
UniProt Related Accession: | P32942 |
Molecular Weight: | 59,541 Da |
NCBI Full Name: | Intercellular adhesion molecule 3 |
NCBI Synonym Full Names: | intercellular adhesion molecule 3 |
NCBI Official Symbol: | ICAM3 |
NCBI Official Synonym Symbols: | CD50; CDW50; ICAM-R |
NCBI Protein Information: | intercellular adhesion molecule 3 |
UniProt Protein Name: | Intercellular adhesion molecule 3 |
UniProt Synonym Protein Names: | CDw50; ICAM-R; CD_antigen: CD50 |
UniProt Gene Name: | ICAM3 |
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