ICAM2 Antibody (PACO02254)
- SKU:
- PACO02254
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ICAM2 Antibody |
抗体コード: | PACO02254 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human ICAM-2. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | ICAM2; Intercellular adhesion molecule 2; ICAM-2; CD102 |
UniProt Protein Function: | ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family. |
UniProt Protein Details: | Protein type:Cell adhesion; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q23.3 Cellular Component: membrane; integral to plasma membrane; plasma membrane; uropod Molecular Function:integrin binding Biological Process: extracellular matrix organization and biogenesis; cell-cell adhesion; regulation of immune response; cell adhesion |
NCBI Summary: | The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P13598 |
NCBI GenInfo Identifier: | 115502404 |
NCBI Gene ID: | 3384 |
NCBI Accession: | P13598.2 |
UniProt Secondary Accession: | P13598,Q14600, |
UniProt Related Accession: | P13598 |
Molecular Weight: | 30,654 Da |
NCBI Full Name: | Intercellular adhesion molecule 2 |
NCBI Synonym Full Names: | intercellular adhesion molecule 2 |
NCBI Official Symbol: | ICAM2 |
NCBI Official Synonym Symbols: | CD102 |
NCBI Protein Information: | intercellular adhesion molecule 2; ICAM-2 |
UniProt Protein Name: | Intercellular adhesion molecule 2 |
UniProt Synonym Protein Names: | CD_antigen: CD102 |
Protein Family: | Intercellular adhesion molecule |
UniProt Gene Name: | ICAM2 |
UniProt Entry Name: | ICAM2_HUMAN |