HUS1B Antibody (PACO62559)
- SKU:
- PACO62559
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HUS1B Antibody (PACO62559) |
抗体コード: | PACO62559 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
反応性: | Human |
免疫原: | Recombinant Human Checkpoint protein HUS1B protein (37-113AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO62559 diluted at 1:400 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | checkpoint clamp complex, site of double-strand break, double-strand break repair via homologous recombination, intra-S DNA damage checkpoint, meiotic DNA integrity checkpoint, mitotic DNA replication checkpoint, nucleotide-excision repair |
シノニム: | Checkpoint protein HUS1B (hHUS1B), HUS1B |
UniProt Protein Function: | HUS1B: is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 6p25.3 Cellular Component: nucleolus Biological Process: DNA damage checkpoint; DNA repair |
NCBI Summary: | The protein encoded by this gene is most closely related to HUS1, a component of a cell cycle checkpoint protein complex involved in cell cycle arrest in response to DNA damage. This protein can interact with the check point protein RAD1 but not with RAD9. Overexpression of this protein has been shown to induce cell death, which suggests a related but distinct role of this protein, as compared to the HUS1. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8NHY5 |
NCBI GenInfo Identifier: | 311033394 |
NCBI Gene ID: | 135458 |
NCBI Accession: | Q8NHY5.2 |
UniProt Secondary Accession: | Q8NHY5,Q5T4Z2, |
UniProt Related Accession: | Q8NHY5 |
Molecular Weight: | 278 |
NCBI Full Name: | Checkpoint protein HUS1B |
NCBI Synonym Full Names: | HUS1 checkpoint homolog b (S. pombe) |
NCBI Official Symbol: | HUS1B |
NCBI Protein Information: | checkpoint protein HUS1B; hHUS1B |
UniProt Protein Name: | Checkpoint protein HUS1B |
Protein Family: | Checkpoint protein |
UniProt Gene Name: | HUS1B |
UniProt Entry Name: | HUS1B_HUMAN |