HSD17B2 Antibody (PACO44175)
- SKU:
- PACO44175
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HSD17B2 Antibody (PACO44175) |
抗体コード: | PACO44175 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Estradiol 17-beta-dehydrogenase 2 protein (118-387AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO44175 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44175 at dilution of 1:100. |
バックグラウンド: | Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. |
シノニム: | Estradiol 17-beta-dehydrogenase 2 (EC 1.1.1.62) (17-beta-hydroxysteroid dehydrogenase type 2) (17-beta-HSD 2) (20 alpha-hydroxysteroid dehydrogenase) (20-alpha-HSD) (E2DH) (Microsomal 17-beta-hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 2) (Testosterone 17-beta-dehydrogenase) (EC 1.1.1.239), HSD17B2, EDH17B2 SDR9C2 |
UniProt Protein Function: | HSD17B2: Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha-HSD activity. Uses NADH while EDH17B3 uses NADPH. Belongs to the short-chain dehydrogenases/reductases (SDR) family. |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.1.1.239; Endoplasmic reticulum; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; EC 1.1.1.62 Chromosomal Location of Human Ortholog: 16q24.1-q24.2 Cellular Component: endoplasmic reticulum membrane Molecular Function:20-alpha-hydroxysteroid dehydrogenase activity; 3-alpha(17-beta)-hydroxysteroid dehydrogenase (NAD+) activity; estradiol 17-beta-dehydrogenase activity Biological Process: response to retinoic acid |
UniProt Code: | P37059 |
NCBI GenInfo Identifier: | 544152 |
NCBI Gene ID: | 3294 |
NCBI Accession: | P37059.1 |
UniProt Secondary Accession: | P37059,B2R7T4, |
UniProt Related Accession: | P37059 |
Molecular Weight: | 42,785 Da |
NCBI Full Name: | Estradiol 17-beta-dehydrogenase 2 |
NCBI Synonym Full Names: | hydroxysteroid 17-beta dehydrogenase 2 |
NCBI Official Symbol: | HSD17B2 |
NCBI Official Synonym Symbols: | HSD17; SDR9C2; EDH17B2 |
NCBI Protein Information: | estradiol 17-beta-dehydrogenase 2 |
UniProt Protein Name: | Estradiol 17-beta-dehydrogenase 2 |
UniProt Synonym Protein Names: | 17-beta-hydroxysteroid dehydrogenase type 2; 17-beta-HSD 2; 20 alpha-hydroxysteroid dehydrogenase; 20-alpha-HSD; E2DH; Microsomal 17-beta-hydroxysteroid dehydrogenase; Short chain dehydrogenase/reductase family 9C member 2; Testosterone 17-beta-dehydrogenase (EC:1.1.1.239) |
Protein Family: | Estradiol 17 beta-dehydrogenase |
UniProt Gene Name: | HSD17B2 |
UniProt Entry Name: | DHB2_HUMAN |