HRH2 Antibody (PACO19788)
- SKU:
- PACO19788
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HRH2 Antibody (PACO19788) |
抗体コード: | PACO19788 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000 |
反応性: | Human |
免疫原: | Synthetic peptide of human HRH2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal muscle tissue, Primary antibody: PACO19788(HRH2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
バックグラウンド: | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid, secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
シノニム: | histamine receptor H2 |
UniProt Protein Function: | H2R: The H2 subclass of histamine receptors mediates gastric acid secretion. Also appears to regulate gastrointestinal motility and intestinal secretion. Possible role in regulating cell growth and differentiation. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and, through a separate G protein-dependent mechanism, the phosphoinositide/protein kinase (PKC) signaling pathway. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1 Chromosomal Location of Human Ortholog: 5q35.2 Cellular Component: integral to plasma membrane; plasma membrane Biological Process: G-protein signaling, coupled to cyclic nucleotide second messenger; immune response |
NCBI Summary: | Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008] |
UniProt Code: | P25021 |
NCBI GenInfo Identifier: | 123120 |
NCBI Gene ID: | 3274 |
NCBI Accession: | P25021.1 |
UniProt Secondary Accession: | P25021,Q14464, Q7Z5R9, B5BUP7, |
UniProt Related Accession: | P25021 |
Molecular Weight: | 44,541 Da |
NCBI Full Name: | Histamine H2 receptor |
NCBI Synonym Full Names: | histamine receptor H2 |
NCBI Official Symbol: | HRH2 |
NCBI Official Synonym Symbols: | H2R |
NCBI Protein Information: | histamine H2 receptor |
UniProt Protein Name: | Histamine H2 receptor |
UniProt Synonym Protein Names: | Gastric receptor I |
Protein Family: | Histamine H2 receptor |
UniProt Gene Name: | HRH2 |
UniProt Entry Name: | HRH2_HUMAN |
Antibodies | ELISA Kits |
Anti-HRH2 Antibody (CAB14170) | Human HRH2 (Histamine H2 receptor)ELISA kit (HUFI03420) |
HRH2 Antibody (PACO02818) | |
HRH2 Antibody (PACO09798) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |