HOXD10 Antibody (PACO04066)
- SKU:
- PACO04066
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HOXD10 Antibody |
抗体コード: | PACO04066 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse |
免疫原: | synthesized peptide derived from the C-terminal region of human HoxD10. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | HOXD10; HOX4D; HOX4E; Homeobox protein Hox-D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E |
UniProt Protein Function: | HOXD10: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Defects in HOXD10 are a cause of congenital vertical talus (CVT); also known as rocker-bottom foot deformity or congenital convex pes valgus. CVT is a dislocation of the talonavicular joint, with rigid dorsal dislocation of the navicular over the neck of the talus. This condition is usually associated with multiple other congenital deformities and only rarely is an isolated deformity. Belongs to the Abd-B homeobox family. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 2q31.1 Disease: Vertical Talus, Congenital |
NCBI Summary: | This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
UniProt Code: | P28358 |
NCBI GenInfo Identifier: | 143811403 |
NCBI Gene ID: | 3236 |
NCBI Accession: | P28358.2 |
UniProt Secondary Accession: | P28358,Q6NT10, |
UniProt Related Accession: | P28358 |
Molecular Weight: | 38,411 Da |
NCBI Full Name: | Homeobox protein Hox-D10 |
NCBI Synonym Full Names: | homeobox D10 |
NCBI Official Symbol: | HOXD10 |
NCBI Official Synonym Symbols: | HOX4; HOX4D; HOX4E; Hox-4.4 |
NCBI Protein Information: | homeobox protein Hox-D10 |
UniProt Protein Name: | Homeobox protein Hox-D10 |
UniProt Synonym Protein Names: | Homeobox protein Hox-4D; Homeobox protein Hox-4E |
Protein Family: | Homeobox protein |
UniProt Gene Name: | HOXD10 |
UniProt Entry Name: | HXD10_HUMAN |