HOOK3 Antibody (PACO09774)
- SKU:
- PACO09774
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HOOK3 Antibody (PACO09774) |
抗体コード: | PACO09774 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human HOOK3 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | hook homolog 3 (Drosophila);HOOK3;FLJ31058;HK3 ; |
UniProt Protein Function: | HOOK3: Probably serves as a target for the spiC protein from Salmonella typhimurium, which inactivates it, leading to a strong alteration in cellular trafficking. Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). May regulate clearance of endocytosed receptors such as MSR1. Participates in defining the architecture and localization of the Golgi complex. Belongs to the hook family. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 8p11.21 Cellular Component: centrosome; cis-Golgi network; cytoplasm; cytosol; Golgi apparatus; microtubule; microtubule organizing center; pericentriolar material Molecular Function:identical protein binding; microtubule binding; protein binding Biological Process: cytoplasmic microtubule organization and biogenesis; early endosome to late endosome transport; endosome organization and biogenesis; endosome to lysosome transport; Golgi localization; interkinetic nuclear migration; lysosome organization and biogenesis; negative regulation of neurogenesis; protein transport |
NCBI Summary: | Hook proteins are cytosolic coiled-coil proteins that contain conserved N-terminal domains, which attach to microtubules, and more divergent C-terminal domains, which mediate binding to organelles. The Drosophila Hook protein is a component of the endocytic compartment.[supplied by OMIM, Apr 2004] |
UniProt Code: | Q86VS8 |
NCBI GenInfo Identifier: | 14165274 |
NCBI Gene ID: | 84376 |
NCBI Accession: | NP_115786.1 |
UniProt Secondary Accession: | Q86VS8,Q8NBH0, Q9BY13, D3DSY8, |
UniProt Related Accession: | Q86VS8 |
Molecular Weight: | 83,126 Da |
NCBI Full Name: | protein Hook homolog 3 |
NCBI Synonym Full Names: | hook microtubule tethering protein 3 |
NCBI Official Symbol: | HOOK3 |
NCBI Official Synonym Symbols: | HK3 |
NCBI Protein Information: | protein Hook homolog 3 |
UniProt Protein Name: | Protein Hook homolog 3 |
Protein Family: | Protein Hook |
UniProt Gene Name: | HOOK3 |
UniProt Entry Name: | HOOK3_HUMAN |