HNRNPM Antibody (PACO20896)
- SKU:
- PACO20896
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HNRNPM Antibody (PACO20896) |
抗体コード: | PACO20896 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human HNRNPM |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20896(HNRNPM Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 6%SDS-PAGE, Lysate: 40 µg, Lane 1-3: 293T, hela and A172 cell, Primary antibody: PACO20896(HNRNPM Antibody) at dilution 1/400 dilution, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO20896(HNRNPM Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid, binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. |
シノニム: | heterogeneous nuclear ribonucleoprotein M |
UniProt Protein Function: | hnRNP M: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding; Receptor, misc.; RNA splicing; Spliceosome; Nucleolus Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: extracellular matrix; integral to plasma membrane; membrane; nuclear matrix; nucleoplasm; paraspeckles; spliceosome Molecular Function:protein binding; protein domain specific binding Biological Process: alternative nuclear mRNA splicing, via spliceosome; fibroblast growth factor receptor signaling pathway; gene expression; nuclear mRNA splicing, via spliceosome |
NCBI Summary: | This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011] |
UniProt Code: | P52272 |
NCBI GenInfo Identifier: | 55977747 |
NCBI Gene ID: | 4670 |
NCBI Accession: | P52272.3 |
UniProt Secondary Accession: | P52272,Q15584, Q8WZ44, Q96H56, Q9BWL9, Q9Y492, |
UniProt Related Accession: | P52272 |
Molecular Weight: | – Da |
NCBI Full Name: | Heterogeneous nuclear ribonucleoprotein M |
NCBI Synonym Full Names: | heterogeneous nuclear ribonucleoprotein M |
NCBI Official Symbol: | HNRNPM |
NCBI Official Synonym Symbols: | CEAR; HNRPM; HTGR1; NAGR1; HNRPM4; HNRNPM4; hnRNP M |
NCBI Protein Information: | heterogeneous nuclear ribonucleoprotein M |
UniProt Protein Name: | Heterogeneous nuclear ribonucleoprotein M |
Protein Family: | Heterogeneous nuclear ribonucleoprotein |
UniProt Gene Name: | HNRNPM |
UniProt Entry Name: | HNRPM_HUMAN |
Antibodies | ELISA Kits |
Anti-HNRNPM Antibody (CAB6937) | hnRNP M Colorimetric Cell-Based ELISA |
HNRNPM Antibody (PACO04394) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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