HNRNPLL Antibody, FITC conjugated (PACO47460)
- SKU:
- PACO47460
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | HNRNPLL Antibody, FITC conjugated (PACO47460) |
抗体コード: | PACO47460 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Heterogeneous nuclear ribonucleoprotein L-like protein (1-72AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. |
シノニム: | Heterogeneous nuclear ribonucleoprotein L-like (hnRNPLL) (Stromal RNA-regulating factor), HNRNPLL, HNRPLL SRRF |
UniProt Protein Function: | HNRPLL: RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC. Interacts with HNRNPL. Up-regulated in stimulated T-cells. Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 2p22.1 Cellular Component: membrane Molecular Function:mRNA binding; protein binding; RNA binding Biological Process: positive regulation of RNA splicing |
NCBI Summary: | HNRNPLL is a master regulator of activation-induced alternative splicing in T cells. In particular, it alters splicing of CD45 (PTPRC; MIM 151460), a tyrosine phosphatase essential for T-cell development and activation (Oberdoerffer et al., 2008 [PubMed 18669861]).[supplied by OMIM, Aug 2008] |
UniProt Code: | Q8WVV9 |
NCBI GenInfo Identifier: | 62286941 |
NCBI Gene ID: | 92906 |
NCBI Accession: | Q8WVV9.1 |
UniProt Secondary Accession: | Q8WVV9,Q53T80, Q5JB51, Q5JB52, Q659B9, Q8IVH5, Q8IVH6 Q96HR5, |
UniProt Related Accession: | Q8WVV9 |
Molecular Weight: | 60kDa |
NCBI Full Name: | Heterogeneous nuclear ribonucleoprotein L-like |
NCBI Synonym Full Names: | heterogeneous nuclear ribonucleoprotein L like |
NCBI Official Symbol: | HNRNPLL |
NCBI Official Synonym Symbols: | SRRF; HNRPLL |
NCBI Protein Information: | heterogeneous nuclear ribonucleoprotein L-like |
UniProt Protein Name: | Heterogeneous nuclear ribonucleoprotein L-like |
UniProt Synonym Protein Names: | Stromal RNA-regulating factor |
Protein Family: | Heterogeneous nuclear ribonucleoprotein |
UniProt Gene Name: | HNRNPLL |