HLTF Antibody (PACO19763)
- SKU:
- PACO19763
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HLTF Antibody (PACO19763) |
抗体コード: | PACO19763 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Synthetic peptide of human HLTF |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19763(HLTF Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO19763(HLTF Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. |
シノニム: | helicase-like transcription factor |
UniProt Protein Function: | SMARCA3: an enzyme with apparent ATP-dependent DNA helicase activity. Belongs to the SNF2/RAD54 helicase family, RAD16 subfamily. Two alternatively spliced human isoforms have been described. |
UniProt Protein Details: | Protein type:Ligase; EC 3.6.1.-; Nucleolus; EC 3.6.4.-; EC 6.3.2.-; Ubiquitin conjugating system; Helicase; EC 6.3.2.19; DNA-binding; Ubiquitin ligase Chromosomal Location of Human Ortholog: 3q25.1-q26.1 Cellular Component: membrane; nucleoplasm; nucleus Molecular Function:DNA binding; protein binding; ubiquitin protein ligase binding Biological Process: regulation of transcription, DNA-dependent |
NCBI Summary: | This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q14527 |
NCBI GenInfo Identifier: | 60390864 |
NCBI Gene ID: | 6596 |
NCBI Accession: | Q14527.2 |
UniProt Secondary Accession: | Q14527,Q14536, Q16051, Q7KYJ6, Q86YA5, Q92652, Q96KM9 D3DNH3, |
UniProt Related Accession: | Q14527 |
Molecular Weight: | 99,919 Da |
NCBI Full Name: | Helicase-like transcription factor |
NCBI Synonym Full Names: | helicase like transcription factor |
NCBI Official Symbol: | HLTF |
NCBI Official Synonym Symbols: | ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3 |
NCBI Protein Information: | helicase-like transcription factor |
UniProt Protein Name: | Helicase-like transcription factor |
UniProt Synonym Protein Names: | DNA-binding protein/plasminogen activator inhibitor 1 regulator; HIP116; RING finger protein 80; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3; Sucrose nonfermenting protein 2-like 3 |
Protein Family: | Helicase-like transcription factor |
UniProt Gene Name: | HLTF |
UniProt Entry Name: | HLTF_HUMAN |