HIP1R Antibody (PACO56828)
- SKU:
- PACO56828
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HIP1R Antibody (PACO56828) |
抗体コード: | PACO56828 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:500-1:1000 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Huntingtin-interacting protein 1-related protein (304-487AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Rat brain tissue. All lanes: HIP1R antibody at 2.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 120, 71 kDa. Observed band size: 120 kDa. |
![]() | IHC image of PACO56828 diluted at 1:800 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO56828 diluted at 1:800 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. |
シノニム: | Huntingtin-interacting protein 1-related protein (HIP1-related protein) (Huntingtin-interacting protein 12) (HIP-12), HIP1R, HIP12 KIAA0655 |
UniProt Protein Function: | HIP1R: Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. Belongs to the SLA2 family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 12q24 Cellular Component: cytoskeleton; intracellular membrane-bound organelle; clathrin-coated vesicle; perinuclear region of cytoplasm; cytoplasm; clathrin coated vesicle membrane; coated pit Molecular Function:protein binding, bridging; protein binding; actin binding; phosphoinositide binding Biological Process: receptor-mediated endocytosis; actin cytoskeleton organization and biogenesis |
UniProt Code: | O75146 |
NCBI GenInfo Identifier: | 13431563 |
NCBI Gene ID: | 9026 |
NCBI Accession: | O75146.2 |
UniProt Related Accession: | O75146 |
Molecular Weight: | |
NCBI Full Name: | Huntingtin-interacting protein 1-related protein |
NCBI Synonym Full Names: | huntingtin interacting protein 1 related |
NCBI Official Symbol: | HIP1R |
NCBI Official Synonym Symbols: | HIP3; HIP12; ILWEQ |
NCBI Protein Information: | huntingtin-interacting protein 1-related protein |
UniProt Protein Name: | Huntingtin-interacting protein 1-related protein |
UniProt Synonym Protein Names: | Huntingtin-interacting protein 12; HIP-12 |
Protein Family: | Huntingtin-interacting protein 1-related protein |
UniProt Gene Name: | HIP1R |
UniProt Entry Name: | HIP1R_HUMAN |