HCRTR1 Antibody (PACO18796)
- SKU:
- PACO18796
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HCRTR1 Antibody (PACO18796) |
抗体コード: | PACO18796 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human HCRTR1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO18796(HCRTR1 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human renal cancer tissue using PACO18796(HCRTR1 Antibody) at dilution 1/100, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. |
シノニム: | Hypocretin (orexin) receptor 1 |
UniProt Protein Function: | HCRTR1: Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p33 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; neuropeptide receptor activity; orexin receptor activity; peptide binding Biological Process: cellular response to hormone stimulus; regulation of circadian sleep/wake cycle, sleep; synaptic transmission |
NCBI Summary: | The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B. [provided by RefSeq, Jan 2009] |
UniProt Code: | O43613 |
NCBI GenInfo Identifier: | 205804177 |
NCBI Gene ID: | 3061 |
NCBI Accession: | O43613.2 |
UniProt Secondary Accession: | O43613,Q9HBV6, A8K3A6, |
UniProt Related Accession: | O43613 |
Molecular Weight: | 47,536 Da |
NCBI Full Name: | Orexin receptor type 1 |
NCBI Synonym Full Names: | hypocretin receptor 1 |
NCBI Official Symbol: | HCRTR1 |
NCBI Official Synonym Symbols: | OX1R |
NCBI Protein Information: | orexin receptor type 1 |
UniProt Protein Name: | Orexin receptor type 1 |
UniProt Synonym Protein Names: | Hypocretin receptor type 1 |
Protein Family: | Orexin receptor |
UniProt Gene Name: | HCRTR1 |
UniProt Entry Name: | OX1R_HUMAN |
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