HAO1 Antibody, FITC conjugated (PACO57578)
- SKU:
- PACO57578
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | HAO1 Antibody, FITC conjugated (PACO57578) |
抗体コード: | PACO57578 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Hydroxyacid, oxidase 1 protein (161-273AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Has 2-hydroxyacid, oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acid, , with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. |
シノニム: | Hydroxyacid, oxidase 1 (HAOX1) (EC 1.1.3.15) (Glycolate oxidase) (GOX), HAO1, GOX1 HAOX1 |
UniProt Protein Function: | HAO1: Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2- hydroxy octanoate. Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.1.3.15; Carbohydrate Metabolism - glyoxylate and dicarboxylate Chromosomal Location of Human Ortholog: 20p12 Cellular Component: peroxisomal matrix; peroxisome Molecular Function:glycolate oxidase activity; FMN binding; glyoxylate oxidase activity; (S)-2-hydroxy-acid oxidase activity; receptor binding Biological Process: glyoxylate metabolic process; response to oxidative stress; glycolate catabolic process; fatty acid alpha-oxidation |
NCBI Summary: | This gene is one of three related genes that have 2-hydroxyacid oxidase activity yet differ in encoded protein amino acid sequence, tissue expression and substrate preference. Subcellular location of the encoded protein is the peroxisome. Specifically, this gene is expressed primarily in liver and pancreas and the encoded protein is most active on glycolate, a two-carbon substrate. The protein is also active on 2-hydroxy fatty acids. The transcript detected at high levels in pancreas may represent an alternatively spliced form or the use of a multiple near-consensus upstream polyadenylation site. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UJM8 |
NCBI GenInfo Identifier: | 13124294 |
NCBI Gene ID: | 54363 |
NCBI Accession: | Q9UJM8.1 |
UniProt Secondary Accession: | Q9UJM8,Q14CQ0, Q9UPZ0, Q9Y3I7, |
UniProt Related Accession: | Q9UJM8 |
Molecular Weight: | 370 |
NCBI Full Name: | Hydroxyacid oxidase 1 |
NCBI Synonym Full Names: | hydroxyacid oxidase (glycolate oxidase) 1 |
NCBI Official Symbol: | HAO1 |
NCBI Official Synonym Symbols: | GOX; GOX1; HAOX1 |
NCBI Protein Information: | hydroxyacid oxidase 1; glycolate oxidase; (S)-2-hydroxy-acid oxidase |
UniProt Protein Name: | Hydroxyacid oxidase 1 |
UniProt Synonym Protein Names: | Glycolate oxidase; GOX |
Protein Family: | Hydroxyacid oxidase |
UniProt Gene Name: | HAO1 |
UniProt Entry Name: | HAOX1_HUMAN |