HACL1 Antibody (PACO16478)
- SKU:
- PACO16478
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | HACL1 Antibody (PACO16478) |
抗体コード: | PACO16478 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human HACL1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO16478(HACL1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human testis tissue, Primary antibody: PACO16478(HACL1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16478(HACL1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | HACL1 (2-hydroxyacyl-CoA lyase 1) is also known as HPCL or 2-HPCL (2-hydroxyphytanoyl-CoA lyase) and is a 578 amino acid, protein. HACL1 is abundantly expressed in liver, and is also expressed in kidney, heart and skeletal muscle, where it is localized to peroxisomes. HACL1 functions in lipid metabolism as well as fatty acid, metabolism and is able to form homotetramers. |
シノニム: | 2-hydroxyacyl-CoA lyase 1 |
UniProt Protein Function: | HACL1: Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. Belongs to the TPP enzyme family. |
UniProt Protein Details: | Protein type:EC 4.1.-.-; Lyase Chromosomal Location of Human Ortholog: 3p25.1 Cellular Component: peroxisomal matrix; peroxisome Molecular Function:carbon-carbon lyase activity; identical protein binding; magnesium ion binding; thiamin pyrophosphate binding; cofactor binding; receptor binding Biological Process: cellular lipid metabolic process; protein oligomerization; fatty acid alpha-oxidation |
UniProt Code: | Q9UJ83 |
NCBI GenInfo Identifier: | 20455027 |
NCBI Gene ID: | 26061 |
NCBI Accession: | Q9UJ83.2 |
UniProt Related Accession: | Q9UJ83 |
Molecular Weight: | 64kDa |
NCBI Full Name: | 2-hydroxyacyl-CoA lyase 1 |
NCBI Synonym Full Names: | 2-hydroxyacyl-CoA lyase 1 |
NCBI Official Symbol: | HACL1 |
NCBI Official Synonym Symbols: | HPCL; HPCL2; PHYH2; 2-HPCL |
NCBI Protein Information: | 2-hydroxyacyl-CoA lyase 1 |
UniProt Protein Name: | 2-hydroxyacyl-CoA lyase 1 |
UniProt Synonym Protein Names: | 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Phytanoyl-CoA 2-hydroxylase 2 |
Protein Family: | 2-hydroxyacyl-CoA lyase |
UniProt Gene Name: | HACL1 |
UniProt Entry Name: | HACL1_HUMAN |