HACD2 Antibody, HRP conjugated (PACO37103)
- SKU:
- PACO37103
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | HACD2 Antibody, HRP conjugated (PACO37103) |
抗体コード: | PACO37103 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 protein (7-41AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the third of the four reactions of the long-chain fatty acid, elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acid, /VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid, elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. |
シノニム: | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 (EC 4.2.1.134) (3-hydroxyacyl-CoA dehydratase 2) (HACD2) (Protein-tyrosine phosphatase-like member B), HACD2, PTPLB |
UniProt Protein Function: | PTPLB: Responsible for the dehydration step in very long-chain fatty acids (VLCFAs) synthesis. Belongs to the very long-chain fatty acids dehydratase HACD family.Protein type: Membrane protein, multi-pass; EC 4.2.1.134; Membrane protein, integral; Lipid Metabolism - unsaturated fatty acid biosynthesisChromosomal Location of Human Ortholog: 3q21.1Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membraneMolecular Function: 3-hydroxyacyl-CoA dehydratase activity; enzyme binding; protein binding; protein tyrosine phosphatase activityBiological Process: cellular lipid metabolic process; fatty acid elongation; sphingolipid biosynthetic process; triacylglycerol biosynthetic process; very-long-chain fatty acid biosynthetic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6Y1H2 |
NCBI GenInfo Identifier: | 38257153 |
NCBI Gene ID: | 201562 |
NCBI Accession: | NP_940684.1 |
UniProt Secondary Accession: | Q6Y1H2 |
UniProt Related Accession: | Q6Y1H2 |
Molecular Weight: | 28,368 Da |
NCBI Full Name: | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 |
NCBI Synonym Full Names: | 3-hydroxyacyl-CoA dehydratase 2 |
NCBI Official Symbol: | HACD2 |
NCBI Official Synonym Symbols: | PTPLB |
NCBI Protein Information: | very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 |
UniProt Protein Name: | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 |
UniProt Synonym Protein Names: | 3-hydroxyacyl-CoA dehydratase 2 |
Protein Family: | |
UniProt Gene Name: | HACD2 |
UniProt Entry Name: | HACD2_HUMAN |