GRAP Antibody (PACO62183)
- SKU:
- PACO62183
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GRAP Antibody (PACO62183) |
抗体コード: | PACO62183 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human GRB2-related adapter protein (1-217AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO62183 diluted at 1:30 and staining in paraffin-embedded human skeletal muscle tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. |
シノニム: | GRB2-related adapter protein, GRAP |
NCBI Summary: | This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligand-activated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCR-ABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its N-terminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway. [provided by RefSeq, Jul 2012] |
UniProt Code: | Q13588 |
NCBI GenInfo Identifier: | 5729856 |
NCBI Gene ID: | 10750 |
NCBI Accession: | NP_006604.1 |
UniProt Related Accession: | Q13588 |
Molecular Weight: | 36kDa |
NCBI Full Name: | GRB2-related adapter protein isoform 1 |
NCBI Synonym Full Names: | GRB2 related adaptor protein |
NCBI Official Symbol: | GRAP |
NCBI Official Synonym Symbols: | DFNB114 |
NCBI Protein Information: | GRB2-related adapter protein |
UniProt Protein Name: | GRB2-related adapter protein |
Protein Family: | GRB2-related adapter protein |
UniProt Gene Name: | GRAP |
UniProt Entry Name: | GRAP_HUMAN |