GPR68 Antibody (PACO44767)
- SKU:
- PACO44767
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GPR68 Antibody (PACO44767) |
抗体コード: | PACO44767 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Ovarian cancer G-protein coupled receptor 1 protein (276-365AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO44767 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO44767 at dilution of 1:100. |
バックグラウンド: | Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acid, sis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity). |
シノニム: | Ovarian cancer G-protein coupled receptor 1 (OGR-1) (G-protein coupled receptor 68) (GPR12A) (Sphingosylphosphorylcholine receptor), GPR68, OGR1 |
UniProt Protein Function: | GPR68: Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca(2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Tumor suppressor; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR Chromosomal Location of Human Ortholog: 14q31 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; inflammatory response; negative regulation of monocyte differentiation |
UniProt Code: | Q15743 |
NCBI GenInfo Identifier: | 3024266 |
NCBI Gene ID: | 8111 |
NCBI Accession: | Q15743.1 |
UniProt Secondary Accession: | Q15743,Q13334, Q4VBB4, Q6IX34, |
UniProt Related Accession: | Q15743 |
Molecular Weight: | 365 |
NCBI Full Name: | Ovarian cancer G-protein coupled receptor 1 |
NCBI Synonym Full Names: | G protein-coupled receptor 68 |
NCBI Official Symbol: | GPR68 |
NCBI Official Synonym Symbols: | OGR1; GPR12A |
NCBI Protein Information: | ovarian cancer G-protein coupled receptor 1; G-protein coupled receptor 68; sphingosylphosphorylcholine receptor; ovarian cancer G protein-coupled receptor, 1 |
UniProt Protein Name: | Ovarian cancer G-protein coupled receptor 1 |
UniProt Synonym Protein Names: | G-protein coupled receptor 68; GPR12A; Sphingosylphosphorylcholine receptor |
Protein Family: | Ovarian cancer G-protein coupled receptor |
UniProt Gene Name: | GPR68 |
UniProt Entry Name: | OGR1_HUMAN |
Antibodies | ELISA Kits |
Anti-GPR68 Antibody (CAB7348) | OGR-1 Colorimetric Cell-Based ELISA |
GPR68 Antibody (PACO05412) |
Secondary Antibody |
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