GPR55 Antibody, Biotin conjugated (PACO63322)
- SKU:
- PACO63322
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | GPR55 Antibody, Biotin conjugated (PACO63322) |
抗体コード: | PACO63322 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Peptide sequence from Human G-protein coupled receptor 55 protein (203-222AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | May be involved in hyperalgesia associated with inflammatory and neuropathic pain (By similarity). Receptor for L-alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. |
シノニム: | G-protein coupled receptor 55, GPR55 |
UniProt Protein Function: | GPR55: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L- alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid receptor. May play a role in bone physiology by regulating osteoclast number and function. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:cannabinoid receptor activity; G-protein coupled receptor activity Biological Process: bone resorption; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); G-protein coupled receptor protein signaling pathway; negative regulation of osteoclast differentiation; phospholipase C activation; positive regulation of Rho protein signal transduction |
NCBI Summary: | This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q9Y2T6 |
NCBI GenInfo Identifier: | 71159390 |
NCBI Gene ID: | 9290 |
NCBI Accession: | Q9Y2T6.2 |
UniProt Secondary Accession: | Q9Y2T6,Q8N580, |
UniProt Related Accession: | Q9Y2T6 |
Molecular Weight: | Calculated MW: 36kDaObserved MW: 37kDa |
NCBI Full Name: | G-protein coupled receptor 55 |
NCBI Synonym Full Names: | G protein-coupled receptor 55 |
NCBI Official Symbol: | GPR55 |
NCBI Official Synonym Symbols: | LPIR1 |
NCBI Protein Information: | G-protein coupled receptor 55 |
UniProt Protein Name: | G-protein coupled receptor 55 |
Protein Family: | G-protein coupled receptor |
UniProt Gene Name: | GPR55 |