GPD1 Antibody, HRP conjugated (PACO27142)
- SKU:
- PACO27142
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | GPD1 Antibody, HRP conjugated (PACO27142) |
抗体コード: | PACO27142 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic protein (1-349AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
シノニム: | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8), GPD1 |
UniProt Protein Function: | GPD1: Defects in GPD1 are a cause of hypertriglyceridemia, transient infantile (HTGTI). An autosomal recessive disorder characterized by onset of moderate to severe transient hypertriglyceridemia in infancy that normalizes with age. The hypertriglyceridemia is associated with hepatomegaly, moderately elevated transaminases, persistent fatty liver, and the development of hepatic fibrosis. Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. |
UniProt Protein Details: | Protein type:Oxidoreductase; EC 1.1.1.8; Lipid Metabolism - glycerophospholipid Chromosomal Location of Human Ortholog: 12q13.12 Cellular Component: cytosol Molecular Function:glycerol-3-phosphate dehydrogenase (NAD+) activity Biological Process: phosphatidic acid biosynthetic process; triacylglycerol biosynthetic process Disease: Hypertriglyceridemia, Transient Infantile |
NCBI Summary: | This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
UniProt Code: | P21695 |
NCBI GenInfo Identifier: | 134047785 |
NCBI Gene ID: | 2819 |
NCBI Accession: | P21695.4 |
UniProt Secondary Accession: | P21695,Q8N1B0, F8W1L5, |
UniProt Related Accession: | P21695 |
Molecular Weight: | 35,140 Da |
NCBI Full Name: | Glycerol-3-phosphate dehydrogenase |
NCBI Synonym Full Names: | glycerol-3-phosphate dehydrogenase 1 |
NCBI Official Symbol: | GPD1 |
NCBI Official Synonym Symbols: | GPD-C; HTGTI; GPDH-C |
NCBI Protein Information: | glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic |
UniProt Protein Name: | Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic |
Protein Family: | Glycerol-3-phosphate dehydrogenase |
UniProt Gene Name: | GPD1 |
UniProt Entry Name: | GPDA_HUMAN |