GPBAR1 Antibody, Biotin conjugated (PACO56025)
- SKU:
- PACO56025
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | GPBAR1 Antibody, Biotin conjugated (PACO56025) |
抗体コード: | PACO56025 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human G-protein coupled bile acid, receptor 1 protein (283-330AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Receptor for bile acid, Bile acid, binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acid,. |
シノニム: | G-protein coupled bile acid, receptor 1 (G-protein coupled receptor GPCR19) (hGPCR19) (Membrane-type receptor for bile acid, ) (M-BAR) (hBG37) (BG37), GPBAR1, TGR5 |
UniProt Protein Function: | Receptor for bile acid. Bile acid-binding induces its internalization, activation of extracellular signal-regulated kinase and intracellular cAMP production. May be involved in the suppression of macrophage functions by bile acids. |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8TDU6 |
NCBI GenInfo Identifier: | 116284384 |
NCBI Gene ID: | 151306 |
NCBI Accession: | NP_001070659.1 |
UniProt Secondary Accession: | Q8TDU6,B3KV35 |
UniProt Related Accession: | Q8TDU6 |
Molecular Weight: | 35,248 Da |
NCBI Full Name: | G-protein coupled bile acid receptor 1 |
NCBI Synonym Full Names: | G protein-coupled bile acid receptor 1 |
NCBI Official Symbol: | GPBAR1 |
NCBI Official Synonym Symbols: | BG37; TGR5; M-BAR; GPCR19; GPR131 |
NCBI Protein Information: | G-protein coupled bile acid receptor 1 |
UniProt Protein Name: | G-protein coupled bile acid receptor 1 |
UniProt Synonym Protein Names: | G-protein coupled receptor GPCR19; hGPCR19; Membrane-type receptor for bile acids; M-BAR; hBG37; BG37 |
Protein Family: | |
UniProt Gene Name: | GPBAR1 |
UniProt Entry Name: |