GOSR2 Antibody (PACO27117)
- SKU:
- PACO27117
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | GOSR2 Antibody (PACO27117) |
抗体コード: | PACO27117 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Golgi SNAP receptor complex member 2 protein (1-190AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: GOSR2 antibody at 4µg/ml + Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 25, 23 kDa Observed band size: 25 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO27117 at dilution of 1:100. |
バックグラウンド: | Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. |
シノニム: | Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin), GOSR2, GS27 |
UniProt Protein Function: | GOSR2: Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network. Defects in GOSR2 are the cause of progressive myoclonic epilepsy type 6 (EPM6). A neurologic disorder characterized by onset of ataxia in the first years of life, followed by action myoclonus and seizures later in childhood, and loss of independent ambulation in the second decade. Cognition is not usually affected, although mild memory difficulties may occur in the third decade. Belongs to the GOSR2 family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Endoplasmic reticulum; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q21 Cellular Component: Golgi membrane; SNARE complex; Golgi apparatus; endoplasmic reticulum membrane; Golgi stack; membrane; late endosome membrane; integral to membrane Molecular Function:SNAP receptor activity; SNARE binding; transporter activity Biological Process: intra-Golgi vesicle-mediated transport; ER to Golgi vesicle-mediated transport; unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; unfolded protein response; Golgi to vacuole transport; vesicle fusion with Golgi apparatus; protein targeting to vacuole; retrograde transport, endosome to Golgi Disease: Epilepsy, Progressive Myoclonic 6 |
NCBI Summary: | This gene encodes a trafficking membrane protein which transports proteins among the medial- and trans-Golgi compartments. Due to its chromosomal location and trafficking function, this gene may be involved in familial essential hypertension. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14653 |
NCBI GenInfo Identifier: | 22654242 |
NCBI Gene ID: | 9570 |
NCBI Accession: | O14653.2 |
UniProt Secondary Accession: | O14653,Q8N4B8, Q96DA5, Q9BZZ4, D3DXJ5, D3DXJ6, |
UniProt Related Accession: | O14653 |
Molecular Weight: | 212 |
NCBI Full Name: | Golgi SNAP receptor complex member 2 |
NCBI Synonym Full Names: | golgi SNAP receptor complex member 2 |
NCBI Official Symbol: | GOSR2 |
NCBI Official Synonym Symbols: | Bos1; EPM6; GS27 |
NCBI Protein Information: | Golgi SNAP receptor complex member 2; membrin; 27 kDa Golgi SNARE protein |
UniProt Protein Name: | Golgi SNAP receptor complex member 2 |
UniProt Synonym Protein Names: | 27 kDa Golgi SNARE protein; Membrin |
Protein Family: | Golgi SNAP receptor complex |
UniProt Gene Name: | GOSR2 |
UniProt Entry Name: | GOSR2_HUMAN |
Antibodies | ELISA Kits |
Anti-GOSR2 Antibody (CAB4321) | Human GOSR2 (Golgi SNAP receptor complex member 2) ELISA Kit (HUFI07853) |
GOSR2 Antibody (PACO09538) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |