GOLPH3 Antibody, FITC conjugated (PACO55292)
- SKU:
- PACO55292
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | GOLPH3 Antibody, FITC conjugated (PACO55292) |
抗体コード: | PACO55292 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Golgi phosphoprotein 3 protein (16-150AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Phosphatidylinositol-4-phosphate-binding protein that links Golgi membranes to the cytoskeleton and may participate in the tensile force required for vesicle budding from the Golgi. Thereby, may play a role in Golgi membrane trafficking and could indirectly give its flattened shape to the Golgi apparatus. May also bind to the coatomer to regulate Golgi membrane trafficking. May play a role in anterograde transport from the Golgi to the plasma membrane and regulate secretion. Has also been involved in the control of the localization of Golgi enzymes through interaction with their cytoplasmic part. May play an indirect role in cell migration. Has also been involved in the modulation of mTOR signaling. May also be involved in the regulation of mitochondrial lipids biosynthesis. |
シノニム: | Golgi phosphoprotein 3 (Coat protein GPP34) (Mitochondrial DNA absence factor) (MIDAS), GOLPH3, GPP34 |
UniProt Protein Function: | GOLPH3: Mediates the cis and medial Golgi localization of mannosyltransferases through direct binding of their cytosolic domains. Involved in modulation of mTOR signaling. Involved in the regulation of mitochondrial lipids, leading to increase of mitochondrial mass. Potential oncogene. Belongs to the GOLPH3/VPS74 family. |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 5p13.3 Cellular Component: cytosol; Golgi apparatus; Golgi cisterna; intracellular membrane-bound organelle; mitochondrion; nucleoplasm; trans-Golgi network Molecular Function:enzyme binding; protein binding Biological Process: cell migration; cell proliferation; gene expression; glycoprotein biosynthetic process; Golgi organization and biogenesis; Golgi to plasma membrane protein transport; Golgi vesicle budding; lamellipodium biogenesis; leukocyte tethering or rolling; negative regulation of apoptosis; positive regulation of protein secretion; positive regulation of TOR signaling pathway; protein retention in Golgi; protein secretion |
NCBI Summary: | The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a peripheral membrane protein of the Golgi stack and may have a regulatory role in Golgi trafficking. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H4A6 |
NCBI GenInfo Identifier: | 50400651 |
NCBI Gene ID: | 64083 |
NCBI Accession: | Q9H4A6.1 |
UniProt Secondary Accession: | Q9H4A6,Q9UIW5, |
UniProt Related Accession: | Q9H4A6 |
Molecular Weight: | 33,811 Da |
NCBI Full Name: | Golgi phosphoprotein 3 |
NCBI Synonym Full Names: | golgi phosphoprotein 3 |
NCBI Official Symbol: | GOLPH3 |
NCBI Official Synonym Symbols: | GOPP1; GPP34; MIDAS; Vps74 |
NCBI Protein Information: | Golgi phosphoprotein 3 |
UniProt Protein Name: | Golgi phosphoprotein 3 |
UniProt Synonym Protein Names: | Coat protein GPP34; Mitochondrial DNA absence factor; MIDAS |
Protein Family: | Golgi phosphoprotein |
UniProt Gene Name: | GOLPH3 |
UniProt Entry Name: | GOLP3_HUMAN |