GNAT2 Antibody, FITC conjugated (PACO61532)
- SKU:
- PACO61532
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | GNAT2 Antibody, FITC conjugated (PACO61532) |
抗体コード: | PACO61532 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Guanine nucleotide-binding protein G(t) subunit alpha-2 protein (2-139AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. |
シノニム: | Guanine nucleotide-binding protein G(t) subunit alpha-2, Transducin alpha-2 chain, GNAT2, GNATC |
UniProt Protein Function: | G-alpha t2: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase. Defects in GNAT2 are the cause of achromatopsia type 4 (ACHM4). Achromatopsia is an autosomal recessively inherited visual disorder that is present from birth and that features the absence of color discrimination. Belongs to the G-alpha family. G(i/o/t/z) subfamily. |
UniProt Protein Details: | Protein type:G protein, heterotrimeric; G protein, heterotrimeric alpha G((i/o/t/z)); G protein Chromosomal Location of Human Ortholog: 1p13.1 Cellular Component: heterotrimeric G-protein complex; photoreceptor inner segment; photoreceptor outer segment; plasma membrane Molecular Function:G-protein beta/gamma-subunit binding; G-protein-coupled receptor binding; GTP binding; GTPase activity; signal transducer activity Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste; detection of light stimulus involved in visual perception; G-protein signaling, coupled to cAMP nucleotide second messenger; protein folding; Wnt receptor signaling pathway, calcium modulating pathway Disease: Achromatopsia 4 |
NCBI Summary: | Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses. The transducin alpha subunits in rods and cones are encoded by separate genes. This gene encodes the alpha subunit in cones. [provided by RefSeq, Jul 2008] |
UniProt Code: | P19087 |
NCBI GenInfo Identifier: | 232151 |
NCBI Gene ID: | 2780 |
NCBI Accession: | P19087.4 |
UniProt Related Accession: | P19087 |
Molecular Weight: | 40,176 Da |
NCBI Full Name: | Guanine nucleotide-binding protein G(t) subunit alpha-2 |
NCBI Synonym Full Names: | G protein subunit alpha transducin 2 |
NCBI Official Symbol: | GNAT2 |
NCBI Official Synonym Symbols: | ACHM4; GNATC |
NCBI Protein Information: | guanine nucleotide-binding protein G(t) subunit alpha-2 |
UniProt Protein Name: | Guanine nucleotide-binding protein G(t) subunit alpha-2 |
UniProt Synonym Protein Names: | Transducin alpha-2 chain |
UniProt Gene Name: | GNAT2 |
UniProt Entry Name: | GNAT2_HUMAN |