GMDS Antibody, Biotin conjugated (PACO57783)
- SKU:
- PACO57783
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | GMDS Antibody, Biotin conjugated (PACO57783) |
抗体コード: | PACO57783 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human GDP-mannose 4,6 dehydratase protein (243-346AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose. |
シノニム: | GDP-mannose 4,6 dehydratase (EC 4.2.1.47) (GDP-D-mannose dehydratase) (GMD), GMDS |
UniProt Protein Function: | GMD: an enzyme that converts GDP-D-mannose to GDP-4-keto-6-D- deoxymannose. Perticipates in the extravasation of activated lymphocytes. |
UniProt Protein Details: | Protein type:Lyase; Carbohydrate Metabolism - fructose and mannose; EC 4.2.1.47; Carbohydrate Metabolism - amino sugar and nucleotide sugar Chromosomal Location of Human Ortholog: 6p25 Cellular Component: cytoplasm Molecular Function:GDP-mannose 4,6-dehydratase activity Biological Process: Notch signaling pathway; GDP-mannose metabolic process; 'de novo' GDP-L-fucose biosynthetic process |
NCBI Summary: | GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009] |
UniProt Code: | O60547 |
NCBI GenInfo Identifier: | 9087147 |
NCBI Gene ID: | 2762 |
NCBI Accession: | O60547.1 |
UniProt Secondary Accession: | O60547,O75357, Q5T954, Q6FH09, Q9UGZ3, Q9UJK9, E9PI88 |
UniProt Related Accession: | O60547 |
Molecular Weight: | 372 |
NCBI Full Name: | GDP-mannose 4,6 dehydratase |
NCBI Synonym Full Names: | GDP-mannose 4,6-dehydratase |
NCBI Official Symbol: | GMDS |
NCBI Official Synonym Symbols: | GMD; SDR3E1 |
NCBI Protein Information: | GDP-mannose 4,6 dehydratase; GDP-D-mannose dehydratase; short chain dehydrogenase/reductase family 3E, member 1 |
UniProt Protein Name: | GDP-mannose 4,6 dehydratase |
UniProt Synonym Protein Names: | GDP-D-mannose dehydratase; GMD |
Protein Family: | GDP-mannose 4,6 dehydratase |
UniProt Gene Name: | GMDS |
UniProt Entry Name: | GMDS_HUMAN |