GLYR1 Antibody (PACO19719)
- SKU:
- PACO19719
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GLYR1 Antibody (PACO19719) |
抗体コード: | PACO19719 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human GLYR1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19719(GLYR1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19719(GLYR1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | GLYR1 encodes a deduced 553-amino acid, protein with a molecular mass of 60.5 kD. GLYR1 contains 2 nuclear localization signals, an N-terminal PWWP domain and an AT-hook, and a C-terminal NAD-binding domain. Western blot, RT-PCR, and immunohistochemistry showed that GLYR1 localizes to the nucleus in a variety of cell lines, with robust expression in mouse macrophage RAW274.7 cells. |
シノニム: | glyoxylate reductase 1 homolog (Arabidopsis) |
UniProt Protein Function: | Putative oxidoreductase that is recruited on chromatin and promotes KDM1B demethylase activity (PubMed:23260659). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664). |
UniProt Code: | Q49A26 |
NCBI GenInfo Identifier: | 862669336 |
NCBI Gene ID: | 84656 |
NCBI Accession: | NP_001295025.1 |
UniProt Secondary Accession: | Q49A26,Q5U632, Q6P1Q2, Q6V3W7, Q9BTI1, Q9BXK2, B4DL47 C9JJ40, C9JJ60, |
UniProt Related Accession: | Q49A26 |
Molecular Weight: | 52,559 Da |
NCBI Full Name: | putative oxidoreductase GLYR1 isoform 2 |
NCBI Synonym Full Names: | glyoxylate reductase 1 homolog |
NCBI Official Symbol: | GLYR1 |
NCBI Official Synonym Symbols: | NP60; BM045; HIBDL; N-PAC |
NCBI Protein Information: | putative oxidoreductase GLYR1 |
UniProt Protein Name: | Putative oxidoreductase GLYR1 |
UniProt Synonym Protein Names: | 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; Nuclear protein NP60; Nuclear protein of 60 kDa |
UniProt Gene Name: | GLYR1 |
Antibodies | ELISA Kits |
Anti-GLYR1 Antibody (CAB9046) | Human GLYR1 (Glyoxylate reductase 1 homolog) ELISA Kit (HUFI04102) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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