GLUD2 Antibody (PACO43012)
- SKU:
- PACO43012
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GLUD2 Antibody (PACO43012) |
抗体コード: | PACO43012 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant Human Glutamate dehydrogenase 2, mitochondrial protein (319-558AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: Glutamate dehydrogenase 2, mitochondrial antibody at 4µg/ml. Lane 1: Mouse brain tissue. Lane 2: 293T whole cell lysate. Lane 3: Rat brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 61 kDa. Observed band size: 61 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO43012 at dilution of 1:100. |
バックグラウンド: | Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. |
シノニム: | Glutamate dehydrogenase 2, mitochondrial (GDH 2) (EC 1.4.1.3), GLUD2, GLUDP1 |
UniProt Protein Function: | GLUD2: Important for recycling the chief excitatory neurotransmitter, glutamate, during neurotransmission. Homohexamer. Expressed in retina, testis and, at a lower level, brain. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - alanine, aspartate and glutamate; Other Amino Acids Metabolism - D-Glutamine and D-glutamate; Amino Acid Metabolism - arginine and proline; EC 1.4.1.3; Mitochondrial; Oxidoreductase; Energy Metabolism - nitrogen Chromosomal Location of Human Ortholog: Xq24-q25 Cellular Component: mitochondrion; cytoplasm Molecular Function:glutamate dehydrogenase activity; glutamate dehydrogenase [NAD(P)+] activity; GTP binding; ADP binding Biological Process: glutamate catabolic process; glutamate metabolic process; glutamate biosynthetic process |
NCBI Summary: | The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.[provided by RefSeq, Jan 2010] |
UniProt Code: | P49448 |
NCBI GenInfo Identifier: | 13432152 |
NCBI Gene ID: | 2747 |
NCBI Accession: | P49448.2 |
UniProt Secondary Accession: | P49448,Q9UDQ4, B2R8G0, |
UniProt Related Accession: | P49448 |
Molecular Weight: | 558 |
NCBI Full Name: | Glutamate dehydrogenase 2, mitochondrial |
NCBI Synonym Full Names: | glutamate dehydrogenase 2 |
NCBI Official Symbol: | GLUD2 |
NCBI Official Synonym Symbols: | GDH2; GLUDP1 |
NCBI Protein Information: | glutamate dehydrogenase 2, mitochondrial; GDH 2; glutamate dehydrogenase pseudogene 1 |
UniProt Protein Name: | Glutamate dehydrogenase 2, mitochondrial |
UniProt Gene Name: | GLUD2 |
UniProt Entry Name: | DHE4_HUMAN |