GLS2 Antibody, FITC conjugated (PACO42076)
- SKU:
- PACO42076
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | GLS2 Antibody, FITC conjugated (PACO42076) |
抗体コード: | PACO42076 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Glutaminase liver isoform, mitochondrial protein (15-602AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. |
シノニム: | Glutaminase liver isoform, mitochondrial (GLS) (EC 3.5.1.2) (L-glutaminase) (L-glutamine amidohydrolase), GLS2, GA |
UniProt Protein Function: | GLS2: Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation. Belongs to the glutaminase family. |
UniProt Protein Details: | Protein type:Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - arginine and proline; EC 3.5.1.2; Energy Metabolism - nitrogen; Hydrolase; Mitochondrial; Other Amino Acids Metabolism - D-Glutamine and D-glutamate Chromosomal Location of Human Ortholog: 12q13.3 Cellular Component: mitochondrial matrix; mitochondrion Molecular Function:glutaminase activity; protein binding Biological Process: amino acid biosynthetic process; amino acid metabolic process; glutamate biosynthetic process; glutamate secretion; glutamine catabolic process; regulation of apoptosis |
NCBI Summary: | The protein encoded by this gene is a mitochondrial phosphate-activated glutaminase that catalyzes the hydrolysis of glutamine to stoichiometric amounts of glutamate and ammonia. Originally thought to be liver-specific, this protein has been found in other tissues as well. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q9UI32 |
NCBI GenInfo Identifier: | 145559477 |
NCBI Gene ID: | 27165 |
NCBI Accession: | Q9UI32.2 |
UniProt Secondary Accession: | Q9UI32,Q8IX91, Q9NYY2, Q9UI31, B7Z8Q9, |
UniProt Related Accession: | Q9UI32 |
Molecular Weight: | 66kDa |
NCBI Full Name: | Glutaminase liver isoform, mitochondrial |
NCBI Synonym Full Names: | glutaminase 2 |
NCBI Official Symbol: | GLS2 |
NCBI Official Synonym Symbols: | GA; GLS; LGA; hLGA |
NCBI Protein Information: | glutaminase liver isoform, mitochondrial |
UniProt Protein Name: | Glutaminase liver isoform, mitochondrial |
UniProt Synonym Protein Names: | L-glutaminase; L-glutamine amidohydrolase |
Protein Family: | Glucosidase |
UniProt Gene Name: | GLS2 |