GLRX Antibody, HRP conjugated (PACO27034)
- SKU:
- PACO27034
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | GLRX Antibody, HRP conjugated (PACO27034) |
抗体コード: | PACO27034 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Glutaredoxin-1 protein (1-106AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. |
シノニム: | Glutaredoxin-1 (Thioltransferase-1) (TTase-1), GLRX, GRX |
UniProt Protein Function: | GLRX1: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. Belongs to the glutaredoxin family. |
UniProt Protein Details: | Protein type:Oxidoreductase Chromosomal Location of Human Ortholog: 5q14 Cellular Component: mitochondrion; nucleus; cytosol Molecular Function:electron carrier activity; protein N-terminus binding; glutathione disulfide oxidoreductase activity Biological Process: cell redox homeostasis; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside and nucleotide metabolic process; positive regulation of membrane potential |
NCBI Summary: | This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011] |
UniProt Code: | P35754 |
NCBI GenInfo Identifier: | 1346143 |
NCBI Gene ID: | 2745 |
NCBI Accession: | P35754.2 |
UniProt Secondary Accession: | P35754,Q3KQS1, Q6ICT1, B2R4L2, |
UniProt Related Accession: | P35754 |
Molecular Weight: | 106 |
NCBI Full Name: | Glutaredoxin-1 |
NCBI Synonym Full Names: | glutaredoxin (thioltransferase) |
NCBI Official Symbol: | GLRX |
NCBI Official Synonym Symbols: | GRX; GRX1 |
NCBI Protein Information: | glutaredoxin-1; TTase-1; thioltransferase-1 |
UniProt Protein Name: | Glutaredoxin-1 |
UniProt Synonym Protein Names: | Thioltransferase-1; TTase-1 |
UniProt Gene Name: | GLRX |
UniProt Entry Name: | GLRX1_HUMAN |