GJC1 Antibody (PACO51554)
- SKU:
- PACO51554
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GJC1 Antibody (PACO51554) |
抗体コード: | PACO51554 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Gap junction gamma-1 protein (247-396AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: A549 whole cell lysate. All lanes: GJC1 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 46 kDa. Observed band size: 46 kDa.. |
![]() | Immunofluorescence staining of Hela cells with PACO51554 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
シノニム: | Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein), GJC1, GJA7 |
UniProt Protein Function: | GJC1: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Belongs to the connexin family. Gamma-type subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 17q21.31 Cellular Component: connexon complex; endoplasmic reticulum membrane; plasma membrane; gap junction; integral to membrane Molecular Function:ion channel activity; gap junction channel activity Biological Process: cardiac muscle development; intercellular junction assembly; synaptic transmission; gap junction assembly; visual perception; muscle contraction; transport; vasculogenesis; cell development |
NCBI Summary: | This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | P36383 |
NCBI GenInfo Identifier: | 226693517 |
NCBI Gene ID: | 10052 |
NCBI Accession: | P36383.2 |
UniProt Secondary Accession: | P36383,Q4VAY0, B3KW68, |
UniProt Related Accession: | P36383 |
Molecular Weight: | 45,470 Da |
NCBI Full Name: | Gap junction gamma-1 protein |
NCBI Synonym Full Names: | gap junction protein, gamma 1, 45kDa |
NCBI Official Symbol: | GJC1 |
NCBI Official Synonym Symbols: | CX45; GJA7 |
NCBI Protein Information: | gap junction gamma-1 protein; connexin 45; connexin-45; gap junction alpha-7 protein |
UniProt Protein Name: | Gap junction gamma-1 protein |
UniProt Synonym Protein Names: | Connexin-45; Cx45; Gap junction alpha-7 protein |
Protein Family: | Gap junction gamma-1 protein |
UniProt Gene Name: | GJC1 |
UniProt Entry Name: | CXG1_HUMAN |