GJB4 Antibody, FITC conjugated (PACO40652)
- SKU:
- PACO40652
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | GJB4 Antibody, FITC conjugated (PACO40652) |
抗体コード: | PACO40652 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Gap junction beta-4 protein (211-266AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
シノニム: | Gap junction beta-4 protein (Connexin-30.3) (Cx30.3), GJB4 |
UniProt Protein Function: | GJB4: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Defects in GJB4 are a cause of erythrokeratodermia variabilis (EKV). EKV is a genodermatosis characterized by the appearance of two independent skin lesions: transient figurate erythematous patches and hyperkeratosis that is usually localized but occasionally occurs in its generalized form. Clinical presentation varies significantly within a family and from one family to another. Palmoplantar keratoderma is present in around 50% of cases. Belongs to the connexin family. Beta-type (group I) subfamily. |
UniProt Protein Details: | Protein type:Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p34.3 Cellular Component: cell junction; nucleolus; nucleus Disease: Erythrokeratodermia Variabilis Et Progressiva |
NCBI Summary: | This gene encodes a transmembrane connexin protein that is a component of gap junctions. Mutations in this gene have been associated with erythrokeratodermia variabilis, progressive symmetric erythrokeratoderma and hearing impairment. [provided by RefSeq, Dec 2009] |
UniProt Code: | Q9NTQ9 |
NCBI GenInfo Identifier: | 12229761 |
NCBI Gene ID: | 127534 |
NCBI Accession: | Q9NTQ9.1 |
UniProt Secondary Accession: | Q9NTQ9,B3KQ82, |
UniProt Related Accession: | Q9NTQ9 |
Molecular Weight: | 30kDa |
NCBI Full Name: | Gap junction beta-4 protein |
NCBI Synonym Full Names: | gap junction protein beta 4 |
NCBI Official Symbol: | GJB4 |
NCBI Official Synonym Symbols: | EKV; CX30.3 |
NCBI Protein Information: | gap junction beta-4 protein |
UniProt Protein Name: | Gap junction beta-4 protein |
UniProt Synonym Protein Names: | Connexin-30.3; Cx30.3 |
Protein Family: | Gap junction beta-4 protein |
UniProt Gene Name: | GJB4 |