GCNT2 Antibody, FITC conjugated (PACO26931)
- SKU:
- PACO26931
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | GCNT2 Antibody, FITC conjugated (PACO26931) |
抗体コード: | PACO26931 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase protein (201-402AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. Isoform C: Determines the expression of the blood group I antigen in erythrocytes. |
シノニム: | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (N-acetylglucosaminyltransferase) (I-branching enzyme) (IGNT), GCNT2, GCNT5 II NACGT1 |
UniProt Protein Function: | GCNT2: Branching enzyme that converts linear into branched poly-N-acetyllactosaminoglycans. Introduces the blood group I antigen during embryonic development. It is closely associated with the development and maturation of erythroid cells. The expression of the blood group I antigen in erythrocytes is determined by isoform C. Belongs to the glycosyltransferase 14 family. 3 isoforms of the human protein are produced by alternative splicing |
UniProt Protein Details: | Protein type:Membrane protein, integral; EC 2.4.1.150 Chromosomal Location of Human Ortholog: 6p24.2 Molecular Function:N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity Biological Process: positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of heterotypic cell-cell adhesion; positive regulation of protein kinase B signaling cascade; protein amino acid glycosylation; transforming growth factor beta receptor signaling pathway Disease: Blood Group, I System |
NCBI Summary: | This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8N0V5 |
NCBI GenInfo Identifier: | 74714686 |
NCBI Gene ID: | 2651 |
NCBI Accession: | Q8N0V5.1 |
UniProt Secondary Accession: | Q8N0V5,Q06430, Q5T4J1, Q5W0E9, Q6T5E5, Q8NFS9, |
UniProt Related Accession: | Q8N0V5 |
Molecular Weight: | 46,531 Da |
NCBI Full Name: | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase |
NCBI Synonym Full Names: | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
NCBI Official Symbol: | GCNT2 |
NCBI Official Synonym Symbols: | II; CCAT; IGNT; ULG3; GCNT5; GCNT2C; NACGT1; NAGCT1; CTRCT13; bA421M1.1; bA360O19.2 |
NCBI Protein Information: | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase |
UniProt Protein Name: | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase |
UniProt Synonym Protein Names: | I-branching enzyme; IGNT |
Protein Family: | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase |
UniProt Gene Name: | GCNT2 |
UniProt Entry Name: | GNT2A_HUMAN |