gag Antibody, HRP conjugated (PACO34643)
- SKU:
- PACO34643
- Product type:
- Antibody
- Reactivity:
- Moloney murine leukemia virus
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | gag Antibody, HRP conjugated (PACO34643) |
抗体コード: | PACO34643 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Moloney murine leukemia virus |
免疫原: | Recombinant Moloney murine leukemia virus Gag polyprotein protein (216-478AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release.Matrix protein p15 targets Gag and gag-pol polyproteins to the plasma membrane via a multipartite membrane binding signal, that includes its myristoylated N-terminus. Also mediates nuclear localization of the preintegration complex.Capsid protein p30 forms the spherical core of the virion that encapsulates the genomic RNA-nucleocapsid complex.Nucleocapsid protein p10 is involved in the packaging and encapsidation of two copies of the genome. Binds with high affinity to conserved UCUG elements within the packaging signal, located near the 5'-end of the genome. This binding is dependent on genome dimerization. |
シノニム: | Gag polyprotein (Pr65gag) (Core polyprotein) [Cleaved into: Matrix protein p15 (MA); RNA-binding phosphoprotein p12 (pp12); Capsid protein p30 (CA); Nucleocapsid protein p10-Gag (NC-gag)], gag |
UniProt Protein Function: | Gag polyprotein plays a role in budding and is processed by the viral protease during virion maturation outside the cell. During budding, it recruits, in a PPXY-dependent or independent manner, Nedd4-like ubiquitin ligases that conjugate ubiquitin molecules to Gag, or to Gag binding host factors. Interaction with HECT ubiquitin ligases probably link the viral protein to the host ESCRT pathway and facilitate release. |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | P03332 |
NCBI GenInfo Identifier: | 9626959 |
NCBI Gene ID: | 1491870 |
NCBI Accession: | NP_057934.1 |
UniProt Secondary Accession: | P03332,Q9WJP4 |
UniProt Related Accession: | P03332 |
Molecular Weight: | 57.6 kDa |
NCBI Full Name: | Pr65 |
NCBI Synonym Full Names: | |
NCBI Official Symbol: | gag |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | Pr65; p15 MA; pp12; p30 CA; p10 NC |
UniProt Protein Name: | Gag polyprotein |
UniProt Synonym Protein Names: | Core polyprotein |
Protein Family: | Gag polyprotein |
UniProt Gene Name: | gag |
UniProt Entry Name: | GAG_MLVMS |