GABRR1 Antibody (PACO44218)
- SKU:
- PACO44218
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | GABRR1 Antibody (PACO44218) |
抗体コード: | PACO44218 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Gamma-aminobutyric acid, receptor subunit rho-1 protein (365-465AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human thymus tissue using PACO44218 at dilution of 1:100. |
バックグラウンド: | GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. |
シノニム: | Gamma-aminobutyric acid, receptor subunit rho-1 (GABA(A) receptor subunit rho-1) (GABA(C) receptor), GABRR1 |
UniProt Protein Function: | GABRR1: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel. Rho-1 GABA receptor could play a role in retinal neurotransmission. Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRR1 sub-subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, misc.; Transporter; Transporter, ion channel; Channel, ligand-gated; Membrane protein, multi-pass; Channel, chloride; Membrane protein, integral Chromosomal Location of Human Ortholog: 6q15 Cellular Component: postsynaptic membrane; integral to plasma membrane; plasma membrane; cell junction Molecular Function:chloride channel activity; GABA-A receptor activity; extracellular ligand-gated ion channel activity Biological Process: synaptic transmission; transport; transmembrane transport; gamma-aminobutyric acid signaling pathway |
NCBI Summary: | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. GABRR1 is a member of the rho subunit family. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012] |
UniProt Code: | P24046 |
NCBI GenInfo Identifier: | 223590210 |
NCBI Gene ID: | 2569 |
NCBI Accession: | P24046.2 |
UniProt Related Accession: | P24046 |
Molecular Weight: | |
NCBI Full Name: | Gamma-aminobutyric acid receptor subunit rho-1 |
NCBI Synonym Full Names: | gamma-aminobutyric acid type A receptor rho1 subunit |
NCBI Official Symbol: | GABRR1 |
NCBI Protein Information: | gamma-aminobutyric acid receptor subunit rho-1 |
UniProt Protein Name: | Gamma-aminobutyric acid receptor subunit rho-1 |
UniProt Synonym Protein Names: | GABA(A) receptor subunit rho-1; GABA(C) receptor |
UniProt Gene Name: | GABRR1 |
UniProt Entry Name: | GBRR1_HUMAN |