FXYD6 Antibody, FITC conjugated (PACO40540)
- SKU:
- PACO40540
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | FXYD6 Antibody, FITC conjugated (PACO40540) |
抗体コード: | PACO40540 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human FXYD domain-containing ion transport regulator 6 protein (59-95AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | integral component of plasma membrane, plasma membrane, sodium channel regulator activity, ion transmembrane transport, regulation of sodium ion transmembrane transporter activity, transmembrane transport |
シノニム: | FXYD domain-containing ion transport regulator 6 (Phosphohippolin), FXYD6 |
UniProt Protein Function: | FXYD6: Genetic variations in FXYD6 are associated with susceptibility to schizophrenia type 2 (SCZD2). A complex, multifactorial psychotic disorder or group of disorders characterized by disturbances in the form and content of thought (e.g. delusions, hallucinations), in mood (e.g. inappropriate affect), in sense of self and relationship to the external world (e.g. loss of ego boundaries, withdrawal), and in behavior (e.g bizarre or apparently purposeless behavior). Although it affects emotions, it is distinguished from mood disorders in which such disturbances are primary. Similarly, there may be mild impairment of cognitive function, and it is distinguished from the dementias in which disturbed cognitive function is considered primary. Some patients manifest schizophrenic as well as bipolar disorder symptoms and are often given the diagnosis of schizoaffective disorder. Belongs to the FXYD family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Channel, misc. Chromosomal Location of Human Ortholog: 11q23.3 Cellular Component: integral to membrane; plasma membrane Molecular Function:ion channel activity Biological Process: transmembrane transport |
NCBI Summary: | This gene encodes a member of the FXYD family of transmembrane proteins. This particular protein encodes phosphohippolin, which likely affects the activity of Na,K-ATPase. Multiple alternatively spliced transcript variants encoding the same protein have been described. Related pseudogenes have been identified on chromosomes 10 and X. Read-through transcripts have been observed between this locus and the downstream sodium/potassium-transporting ATPase subunit gamma (FXYD2, GeneID 486) locus.[provided by RefSeq, Feb 2011] |
UniProt Code: | Q9H0Q3 |
NCBI GenInfo Identifier: | 20138342 |
NCBI Gene ID: | 53826 |
NCBI Accession: | Q9H0Q3.1 |
UniProt Secondary Accession: | Q9H0Q3,Q6FIG9, Q6UW52, A8K0R4, J3QLD2, |
UniProt Related Accession: | Q9H0Q3 |
Molecular Weight: | 95 |
NCBI Full Name: | FXYD domain-containing ion transport regulator 6 |
NCBI Synonym Full Names: | FXYD domain containing ion transport regulator 6 |
NCBI Official Symbol: | FXYD6 |
NCBI Protein Information: | FXYD domain-containing ion transport regulator 6; phosphohippolin |
UniProt Protein Name: | FXYD domain-containing ion transport regulator 6 |
UniProt Synonym Protein Names: | Phosphohippolin |
Protein Family: | FXYD domain-containing ion transport regulator |
UniProt Gene Name: | FXYD6 |
UniProt Entry Name: | FXYD6_HUMAN |