FUT8 Antibody (PACO19680)
- SKU:
- PACO19680
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| 抗体名: | FUT8 Antibody (PACO19680) |
| 抗体コード: | PACO19680 |
| サイズ: | 50ul |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 |
| 反応性: | Human, Mouse |
| 免疫原: | Synthetic peptide of human FUT8 |
| 憲法: | Liquid |
| ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| 精製方法: | Antigen affinity purification |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO19680(FUT8 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-2: LoVo cells, PC3 cells, Primary antibody: PACO19680(FUT8 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO19680(FUT8 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| バックグラウンド: | This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants |
| シノニム: | fucosyltransferase 8 (α (1,6) fucosyltransferase) |
| UniProt Protein Function: | FUT8: Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:EC 2.4.1.68; Glycan Metabolism - N-glycan biosynthesis; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Motility/polarity/chemotaxis; Transferase Chromosomal Location of Human Ortholog: 14q23.3 Cellular Component: cytosol; Golgi membrane; membrane Molecular Function:glycoprotein 6-alpha-L-fucosyltransferase activity Biological Process: GDP-L-fucose metabolic process; N-glycan processing; oligosaccharide biosynthetic process; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine |
| NCBI Summary: | This gene encodes an enzyme belonging to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2011] |
| UniProt Code: | Q9BYC5 |
| NCBI GenInfo Identifier: | 20138326 |
| NCBI Gene ID: | 2530 |
| NCBI Accession: | Q9BYC5.2 |
| UniProt Secondary Accession: | Q9BYC5,O00235, Q8IUA5, Q9BYC6, Q9P2U5, Q9P2U6, B4DFS7 G3V5N0, |
| UniProt Related Accession: | Q9BYC5 |
| Molecular Weight: | Calculated MW: 19kDa/35kDa/47kDa/66kDaObserved MW: 75kDa |
| NCBI Full Name: | Alpha-(1,6)-fucosyltransferase |
| NCBI Synonym Full Names: | fucosyltransferase 8 |
| NCBI Official Symbol: | FUT8 |
| NCBI Protein Information: | alpha-(1,6)-fucosyltransferase |
| UniProt Protein Name: | Alpha-(1,6)-fucosyltransferase |
| UniProt Synonym Protein Names: | Fucosyltransferase 8; GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase; GDP-fucose--glycoprotein fucosyltransferase; Glycoprotein 6-alpha-L-fucosyltransferase |
| Protein Family: | Probable fucosyltransferase |
| UniProt Gene Name: | FUT8 |