FOXI1 Antibody (PACO52382)
- SKU:
- PACO52382
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FOXI1 Antibody (PACO52382) |
抗体コード: | PACO52382 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Forkhead box protein I1 protein (183-343AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: HepG2 whole cell lysate, A549 whole cell lysate. All lanes: FOXI1 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 41, 31 kDa. Observed band size: 41 kDa. |
![]() | Immunofluorescent analysis of Hela cells using PACO52382 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity). |
シノニム: | Forkhead box protein I1 (Forkhead-related protein FKHL10) (Forkhead-related transcription factor 6) (FREAC-6) (Hepatocyte nuclear factor 3 forkhead homolog 3) (HFH-3) (HNF-3/fork-head homolog 3), FOXI1, FKHL10 FREAC6 |
UniProt Protein Function: | FOXI1: Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 5q34 Cellular Component: nucleus Molecular Function:sequence-specific DNA binding; transcription factor activity Biological Process: positive regulation of transcription from RNA polymerase II promoter Disease: Deafness, Autosomal Recessive 4, With Enlarged Vestibular Aqueduct; Pendred Syndrome |
NCBI Summary: | This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q12951 |
NCBI GenInfo Identifier: | 150421552 |
NCBI Gene ID: | 2299 |
NCBI Accession: | Q12951.3 |
UniProt Secondary Accession: | Q12951,Q14518, Q66SR7, Q8N6L8, |
UniProt Related Accession: | Q12951 |
Molecular Weight: | 30,814 Da |
NCBI Full Name: | Forkhead box protein I1 |
NCBI Synonym Full Names: | forkhead box I1 |
NCBI Official Symbol: | FOXI1 |
NCBI Official Synonym Symbols: | HFH3; FKH10; HFH-3; FKHL10; FREAC6; FREAC-6 |
NCBI Protein Information: | forkhead box protein I1 |
UniProt Protein Name: | Forkhead box protein I1 |
UniProt Synonym Protein Names: | Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FREAC-6; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH-3; HNF-3/fork-head homolog 3 |
Protein Family: | Forkhead box protein |
UniProt Gene Name: | FOXI1 |
UniProt Entry Name: | FOXI1_HUMAN |