FKBP3 Antibody, HRP conjugated (PACO26778)
- SKU:
- PACO26778
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | FKBP3 Antibody, HRP conjugated (PACO26778) |
抗体コード: | PACO26778 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Peptidyl-prolyl cis-trans isomerase FKBP3 protein (2-224AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins. |
シノニム: | Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase), FKBP3, FKBP25 |
UniProt Protein Function: | FKBP3: FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins. Belongs to the FKBP-type PPIase family. |
UniProt Protein Details: | Protein type:Isomerase; EC 5.2.1.8 Chromosomal Location of Human Ortholog: 14q21.2 Cellular Component: endoplasmic reticulum membrane; nucleus Molecular Function:protein binding; peptidyl-prolyl cis-trans isomerase activity; FK506 binding; receptor activity Biological Process: protein peptidyl-prolyl isomerization |
NCBI Summary: | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008] |
UniProt Code: | Q00688 |
NCBI GenInfo Identifier: | 232096 |
NCBI Gene ID: | 2287 |
NCBI Accession: | Q00688.1 |
UniProt Secondary Accession: | Q00688,Q14317, B2R4Q9, |
UniProt Related Accession: | Q00688 |
Molecular Weight: | 224 |
NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase FKBP3 |
NCBI Synonym Full Names: | FK506 binding protein 3, 25kDa |
NCBI Official Symbol: | FKBP3 |
NCBI Official Synonym Symbols: | FKBP-3; FKBP25; PPIase; FKBP-25 |
NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase FKBP3; rotamase; 25 kDa FKBP; PPIase FKBP3; immunophilin FKBP25; rapamycin binding protein; 25 kDa FK506-binding protein; FK506-binding protein 3 (25kD); FK506-binding protein 25, T-cell; rapamycin-selective 25 kDa immunophilin |
UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase FKBP3 |
UniProt Synonym Protein Names: | 25 kDa FK506-binding protein; 25 kDa FKBP; FKBP-25; FK506-binding protein 3; FKBP-3; Immunophilin FKBP25; Rapamycin-selective 25 kDa immunophilin; Rotamase |
Protein Family: | FK506-binding protein |
UniProt Gene Name: | FKBP3 |
UniProt Entry Name: | FKBP3_HUMAN |