FCHO2 Antibody, HRP conjugated (PACO49167)
- SKU:
- PACO49167
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | FCHO2 Antibody, HRP conjugated (PACO49167) |
抗体コード: | PACO49167 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human F-BAR domain only protein 2 protein (100-203AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Functions in an early step of clathrin-mediated endocytosis. Has both a membrane binding/bending activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a lipid-binding activity with a preference for membranes enriched in phosphatidylserine and phosphoinositides (Pi(4,5) biphosphate) like the plasma membrane. Its membrane-bending activity might be important for the subsequent action of clathrin and adaptors in the formation of clathrin-coated vesicles. Involved in adaptor protein complex AP-2-dependent endocytosis of the transferin receptor, it also functions in the AP-2-independent endocytosis of the LDL receptor. |
シノニム: | F-BAR domain only protein 2, FCHO2 |
UniProt Protein Function: | FCHO2: a member of the Tubby-like proteins (TULPs) family, putative transcription factors which share similar 260 amino acid 'tubby domains' at their C-termini. Two alternatively spliced isoforms have been described. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 5q13.2 Cellular Component: clathrin-coated vesicle; coated pit; plasma membrane Molecular Function:phosphatidylinositol-4,5-bisphosphate binding; phosphatidylserine binding; phosphoinositide binding; protein binding Biological Process: clathrin cage assembly; membrane invagination |
UniProt Code: | Q0JRZ9 |
NCBI GenInfo Identifier: | 119369487 |
NCBI Gene ID: | 115548 |
NCBI Accession: | Q0JRZ9.2 |
UniProt Secondary Accession: | Q0JRZ9,Q0JTJ3, Q96CF5, A8K6W7, B2RNQ9, B4DHK0, E9PG79 |
UniProt Related Accession: | Q0JRZ9 |
Molecular Weight: | 85,146 Da |
NCBI Full Name: | F-BAR domain only protein 2 |
NCBI Synonym Full Names: | FCH domain only 2 |
NCBI Official Symbol: | FCHO2 |
NCBI Protein Information: | F-BAR domain only protein 2 |
UniProt Protein Name: | F-BAR domain only protein 2 |
Protein Family: | F-BAR domain only protein |
UniProt Gene Name: | FCHO2 |
UniProt Entry Name: | FCHO2_HUMAN |