FCGR3B Antibody (PACO58753)
- SKU:
- PACO58753
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FCGR3B Antibody (PACO58753) |
抗体コード: | PACO58753 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Low affinity immunoglobulin γ Fc region receptor III-B protein (18-125AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of A549 cells with PACO58753 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. |
シノニム: | Low affinity immunoglobulin γ Fc region receptor III-B (Fc-γ RIII-beta) (Fc-γ RIII) (Fc-γ RIIIb) (FcRIII) (FcRIIIb) (FcR-10) (IgG Fc receptor III-1) (CD antigen CD16b), FCGR3B, CD16B FCG3 FCGR3 IGFR3 |
UniProt Protein Function: | Receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils. |
NCBI Summary: | The protein encoded by this gene is a low affinity receptor for the Fc region of gamma immunoglobulins (IgG). The encoded protein acts as a monomer and can bind either monomeric or aggregated IgG. This gene may function to capture immune complexes in the peripheral circulation. Several transcript variants encoding different isoforms have been found for this gene. A highly-similar gene encoding a related protein is also found on chromosome 1. [provided by RefSeq, Aug 2012] |
UniProt Code: | O75015 |
NCBI GenInfo Identifier: | 7994572 |
NCBI Gene ID: | 2215 |
NCBI Accession: | O75015.2 |
UniProt Related Accession: | O75015 |
Molecular Weight: | |
NCBI Full Name: | Low affinity immunoglobulin gamma Fc region receptor III-B |
NCBI Synonym Full Names: | Fc fragment of IgG receptor IIIb |
NCBI Official Symbol: | FCGR3B |
NCBI Official Synonym Symbols: | CD16; FCG3; CD16A; CD16b; FCGR3; FCGR3A; FCR-10; FCRIII; FCRIIIb |
NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor III-B |
UniProt Protein Name: | Low affinity immunoglobulin gamma Fc region receptor III-B |
UniProt Synonym Protein Names: | Fc-gamma RIII-beta; Fc-gamma RIII; Fc-gamma RIIIb; FcRIII; FcRIIIb; FcR-10; IgG Fc receptor III-1; CD_antigen: CD16b |
UniProt Gene Name: | FCGR3B |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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