FCGR2C Antibody (PACO05689)
- SKU:
- PACO05689
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FCGR2C Antibody (PACO05689) |
抗体コード: | PACO05689 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000 |
反応性: | Human |
免疫原: | Synthesized peptide derived from the C-terminal region of human CD32-C. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | FCGR2C; CD32; FCG2; IGFR2; Low affinity immunoglobulin γ Fc region receptor II-c; IgG Fc receptor II-c; CDw32; Fc-γ RII-c; Fc-γ-RIIc; FcRII-c; CD antigen CD32 |
UniProt Protein Function: | FCGR2C: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed. |
UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Membrane protein, integral Chromosomal Location of Human Ortholog: 1q23.3 Cellular Component: cytoplasm; plasma membrane; integral to membrane Molecular Function:protein binding; transmembrane receptor activity; IgG binding Biological Process: immune response; signal transduction Disease: Thrombocytopenic Purpura, Autoimmune |
NCBI Summary: | This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012] |
UniProt Code: | P31995 |
NCBI GenInfo Identifier: | 399478 |
NCBI Gene ID: | 9103 |
NCBI Accession: | P31995.1 |
UniProt Secondary Accession: | P31995,O00523, O00524, O00525, |
UniProt Related Accession: | P31995 |
Molecular Weight: | 35,578 Da |
NCBI Full Name: | Low affinity immunoglobulin gamma Fc region receptor II-c |
NCBI Synonym Full Names: | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
NCBI Official Symbol: | FCGR2C |
NCBI Official Synonym Symbols: | CD32; FCG2; CD32C; CDW32; IGFR2; FCRIIC |
NCBI Protein Information: | low affinity immunoglobulin gamma Fc region receptor II-c; fc-gamma-RIIc; IgG Fc receptor II-c; Fc gamma receptor IIC; immunoglobulin G Fc receptor II-c |
UniProt Protein Name: | Low affinity immunoglobulin gamma Fc region receptor II-c |
UniProt Synonym Protein Names: | CDw32; Fc-gamma RII-c |
Protein Family: | Low affinity immunoglobulin gamma Fc region receptor |
UniProt Gene Name: | FCGR2C |
UniProt Entry Name: | FCG2C_HUMAN |