FBXW2 Antibody, FITC conjugated (PACO42420)
- SKU:
- PACO42420
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | FBXW2 Antibody, FITC conjugated (PACO42420) |
抗体コード: | PACO42420 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human F-box/WD repeat-containing protein 2 protein (72-340AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. |
シノニム: | F-box/WD repeat-containing protein 2 (F-box and WD-40 domain-containing protein 2) (Protein MD6), FBXW2, FBW2 FWD2 |
UniProt Protein Function: | FBXW2: Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system Chromosomal Location of Human Ortholog: 9q34 Molecular Function:protein binding; ubiquitin-protein ligase activity Biological Process: protein modification process; protein ubiquitination; proteolysis |
NCBI Summary: | F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UKT8 |
NCBI GenInfo Identifier: | 118402584 |
NCBI Gene ID: | 26190 |
NCBI Accession: | NP_036296.2 |
UniProt Secondary Accession: | Q9UKT8,Q4VXH2, Q7Z4V6, Q8WV51, Q9HA09, Q9UKA3, B3KRL8 |
UniProt Related Accession: | Q9UKT8 |
Molecular Weight: | 44,466 Da |
NCBI Full Name: | F-box/WD repeat-containing protein 2 |
NCBI Synonym Full Names: | F-box and WD repeat domain containing 2 |
NCBI Official Symbol: | FBXW2 |
NCBI Official Synonym Symbols: | Md6; FBW2; Fwd2 |
NCBI Protein Information: | F-box/WD repeat-containing protein 2 |
UniProt Protein Name: | F-box/WD repeat-containing protein 2 |
UniProt Synonym Protein Names: | F-box and WD-40 domain-containing protein 2; Protein MD6 |
Protein Family: | F-box/WD repeat-containing protein |
UniProt Gene Name: | FBXW2 |
UniProt Entry Name: | FBXW2_HUMAN |