FBXO8 Antibody (PACO09259)
- SKU:
- PACO09259
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FBXO8 Antibody (PACO09259) |
抗体コード: | PACO09259 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human FBXO8 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | F-box protein 8;FBXO8;DC10;FBS;FBX8 ; |
UniProt Protein Function: | FBXO8: an F-box protein that apparently mediates the ubiquitination of Arf6. May function as a guanine nucleotide exchange factor (GEF) that activates ARF G proteins. The loss of FBXO8 correlates with poor survival in hepatocellular carcinoma. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system; GEFs; GEFs, ARF Chromosomal Location of Human Ortholog: 4q34.1 |
NCBI Summary: | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It contains a C-terminal amino acid sequence that bears a significant similarity with a portion of yeast Sec7p, a critical regulator of vesicular protein transport. This human protein may interact with ADP-ribosylation factor(s)(ARFs) and exhibit ARF-GEF (guanine nucleotide exchange factor) activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NRD0 |
NCBI GenInfo Identifier: | 13124142 |
NCBI Gene ID: | 26269 |
NCBI Accession: | Q9NRD0.1 |
UniProt Secondary Accession: | Q9NRD0,Q6UWN4, Q8IWE1, Q9NRP5, Q9UKC4, B2RB40, D3DP41 G5E9Z0, |
UniProt Related Accession: | Q9NRD0 |
Molecular Weight: | 32,426 Da |
NCBI Full Name: | F-box only protein 8 |
NCBI Synonym Full Names: | F-box protein 8 |
NCBI Official Symbol: | FBXO8 |
NCBI Official Synonym Symbols: | FBS; DC10; FBX8 |
NCBI Protein Information: | F-box only protein 8 |
UniProt Protein Name: | F-box only protein 8 |
UniProt Synonym Protein Names: | F-box/SEC7 protein FBS |
Protein Family: | F-box only protein |
UniProt Gene Name: | FBXO8 |
UniProt Entry Name: | FBX8_HUMAN |