FAT4 Antibody, FITC conjugated (PACO46648)
- SKU:
- PACO46648
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | FAT4 Antibody, FITC conjugated (PACO46648) |
抗体コード: | PACO46648 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protocadherin Fat 4 protein (4658-4862AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Cadherins are calcium-dependent cell adhesion proteins. FAT4 plays a role in the maintenance of planar cell polarity as well as in inhibition of YAP1-mediated neuroprogenitor cell proliferation and differentiation (By similarity). |
シノニム: | Protocadherin Fat 4 (hFat4) (Cadherin family member 14) (FAT tumor suppressor homolog 4) (Fat-like cadherin protein FAT-J), FAT4, CDHF14 FATJ |
UniProt Protein Function: | FAT4: May function in the regulation of planar cell polarity. Cadherins are cell-cell interaction molecules. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 4q28.1 Cellular Component: apical part of cell; integral to membrane; intracellular; plasma membrane Molecular Function:calcium ion binding; protein binding Biological Process: cerebral cortex development; gut development; heart morphogenesis; heterophilic cell adhesion; homophilic cell adhesion; inner ear receptor stereocilium organization and biogenesis; neurogenesis; plasma membrane organization and biogenesis; ureteric bud branching Disease: Hennekam Lymphangiectasia-lymphedema Syndrome 2; Van Maldergem Syndrome 2 |
NCBI Summary: | The protein encoded by this gene is a member of the protocadherin family. This gene may play a role in regulating planar cell polarity (PCP). Studies in mice suggest that loss of PCP signaling may cause cystic kidney disease, and mutations in this gene have been associated with Van Maldergem Syndrome 2. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Mar 2014] |
UniProt Code: | Q6V0I7 |
NCBI GenInfo Identifier: | 603844373 |
NCBI Gene ID: | 79633 |
NCBI Accession: | NP_001278214.1 |
UniProt Secondary Accession: | Q6V0I7,Q3LIA6, Q8TCK7, Q9H5T6, A8K5Z6, B5MDG4, |
UniProt Related Accession: | Q6V0I7 |
Molecular Weight: | 542687 Da |
NCBI Full Name: | protocadherin Fat 4 isoform 2 |
NCBI Synonym Full Names: | FAT atypical cadherin 4 |
NCBI Official Symbol: | FAT4 |
NCBI Official Synonym Symbols: | FATJ; FAT-J; CDHF14; CDHR11; HKLLS2; VMLDS2; NBLA00548 |
NCBI Protein Information: | protocadherin Fat 4 |
UniProt Protein Name: | Protocadherin Fat 4 |
UniProt Synonym Protein Names: | Cadherin family member 14; FAT tumor suppressor homolog 4; Fat-like cadherin protein FAT-J |
Protein Family: | Protocadherin |
UniProt Gene Name: | FAT4 |
UniProt Entry Name: | FAT4_HUMAN |