FARP1 Antibody, HRP conjugated (PACO42839)
- SKU:
- PACO42839
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | FARP1 Antibody, HRP conjugated (PACO42839) |
抗体コード: | PACO42839 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human FERM, ARHGEF and pleckstrin domain-containing protein 1 protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses. |
シノニム: | FERM, ARHGEF and pleckstrin domain-containing protein 1 (Chondrocyte-derived ezrin-like protein) (FERM, RhoGEF and pleckstrin domain-containing protein 1) (Pleckstrin homology domain-containing family C member 2) (PH domain-containing family C member 2), FARP1, CDEP PLEKHC2 |
UniProt Protein Function: | FARP1: May function as Rho-guanine nucleotide exchange factor. 3 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs, Rac/Rho; GEFs; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 13q32.2Cellular Component: cytoplasm; cytosol; dendrite; extrinsic to internal side of plasma membraneMolecular Function: Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activityBiological Process: dendrite morphogenesis; synaptogenesis |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a protein containing a FERM (4.2, exrin, radixin, moesin) domain, a Dbl homology domain, and two pleckstrin homology domains. These domains are found in guanine nucleotide exchange factors and proteins that link the cytoskeleton to the cell membrane. The encoded protein functions in neurons to promote dendritic growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013] |
UniProt Code: | Q9Y4F1 |
NCBI GenInfo Identifier: | 74762059 |
NCBI Gene ID: | 10160 |
NCBI Accession: | Q9Y4F1.1 |
UniProt Secondary Accession: | Q9Y4F1,Q5JVI9, Q6IQ29 |
UniProt Related Accession: | Q9Y4F1 |
Molecular Weight: | 14,138 Da |
NCBI Full Name: | FERM, RhoGEF and pleckstrin domain-containing protein 1 |
NCBI Synonym Full Names: | FERM, ARH/RhoGEF and pleckstrin domain protein 1 |
NCBI Official Symbol: | FARP1 |
NCBI Official Synonym Symbols: | CDEP; PLEKHC2; PPP1R75; FARP1-IT1 |
NCBI Protein Information: | FERM, RhoGEF and pleckstrin domain-containing protein 1 |
UniProt Protein Name: | FERM, RhoGEF and pleckstrin domain-containing protein 1 |
UniProt Synonym Protein Names: | Chondrocyte-derived ezrin-like protein; Pleckstrin homology domain-containing family C member 2; PH domain-containing family C member 2 |
Protein Family: | FERM, RhoGEF and pleckstrin domain-containing protein |
UniProt Gene Name: | FARP1 |
UniProt Entry Name: | FARP1_HUMAN |