FAM35A Antibody (PACO04646)
- SKU:
- PACO04646
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | FAM35A Antibody |
抗体コード: | PACO04646 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human FAM35A/B. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | FAM35A; Protein FAM35A; FAM35B; Protein FAM35B |
UniProt Protein Function: | Component of the shieldin complex, which plays an important role in repair of DNA double-stranded breaks (DSBs) (PubMed:29656893, PubMed:29789392). During G1 and S phase of the cell cycle, the complex functions downstream of TP53BP1 to promote non-homologous end joining (NHEJ) and suppress DNA end resection (PubMed:29656893, PubMed:29789392). Mediates various NHEJ-dependent processes including immunoglobulin class-switch recombination, and fusion of unprotected telomeres (PubMed:29656893). |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q86V20 |
NCBI GenInfo Identifier: | 1052785544 |
NCBI Gene ID: | 54537 |
NCBI Accession: | NP_001317041.1 |
UniProt Secondary Accession: | Q86V20,O95885, Q9H991 |
UniProt Related Accession: | Q86V20 |
Molecular Weight: | 94 KD |
NCBI Full Name: | shieldin complex subunit 2 isoform 1 |
NCBI Synonym Full Names: | shieldin complex subunit 2 |
NCBI Official Symbol: | SHLD2 |
NCBI Official Synonym Symbols: | RINN2; FAM35A; FAM35A1; bA163M19.1 |
NCBI Protein Information: | shieldin complex subunit 2; protein FAM35A |
UniProt Protein Name: | Shieldin complex subunit 2 |
UniProt Synonym Protein Names: | Protein FAM35A |
Protein Family: | |
UniProt Gene Name: | SHLD2 |
UniProt Entry Name: |