UniProt Protein Function: | FABP3: FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 1p33-p32 Cellular Component: extracellular space; sarcoplasm; cytosol Molecular Function:protein binding; icosatetraenoic acid binding; cytoskeletal protein binding; long-chain fatty acid transporter activity Biological Process: response to drug; negative regulation of cell proliferation; cholesterol homeostasis; regulation of fatty acid oxidation; fatty acid metabolic process; response to insulin stimulus; phospholipid homeostasis |
NCBI Summary: | The intracellular fatty acid-binding proteins (FABPs) belongs to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
UniProt Code: | P05413 |
NCBI GenInfo Identifier: | 119802 |
NCBI Gene ID: | 2170 |
NCBI Accession: | P05413.4 |
UniProt Related Accession: | P05413 |
Molecular Weight: | 14858 |
NCBI Full Name: | Fatty acid-binding protein, heart |
NCBI Synonym Full Names: | fatty acid binding protein 3 |
NCBI Official Symbol: | FABP3 |
NCBI Official Synonym Symbols: | MDGI; FABP11; H-FABP; M-FABP; O-FABP |
NCBI Protein Information: | fatty acid-binding protein, heart |
UniProt Protein Name: | Fatty acid-binding protein, heart |
UniProt Synonym Protein Names: | Fatty acid-binding protein 3; Heart-type fatty acid-binding protein; H-FABP; Mammary-derived growth inhibitor; MDGI; Muscle fatty acid-binding protein; M-FABP |
Protein Family: | Fatty acid-binding protein |
UniProt Gene Name: | FABP3 |
UniProt Entry Name: | FABPH_HUMAN |