ETS2 Antibody (PACO48326)
- SKU:
- PACO48326
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ETS2 Antibody (PACO48326) |
抗体コード: | PACO48326 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Protein C-ets-2 protein (9-185AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Hela whole cell lysate, MCF-7 whole cell lysate, Mouse liver tissue, Mouse brain tissue. All lanes: ETS2 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 54 kDa. Observed band size: 54 kDa.. |
バックグラウンド: | Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription. |
シノニム: | Protein C-ets-2, ETS2 |
UniProt Protein Function: | Ets-2: a proto-oncogenic transcription factor homologous to the v-ets erythroblastosis virus E26 oncogene. A target of the Akt/JNK signaling pathway in macrophages. A PKC pathway activates ETS2, up-regulating GM-CSF in non-small lung carcinoma cells. |
UniProt Protein Details: | Protein type:Transcription factor; Oncoprotein; DNA-binding Chromosomal Location of Human Ortholog: 21q22.2 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; DNA binding; transcription factor activity; glucocorticoid receptor binding Biological Process: transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription from RNA polymerase II promoter; cell differentiation; skeletal development |
NCBI Summary: | This gene encodes a transcription factor which regulates genes involved in development and apoptosis. The encoded protein is also a protooncogene and shown to be involved in regulation of telomerase. A pseudogene of this gene is located on the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012] |
UniProt Code: | P15036 |
NCBI GenInfo Identifier: | 119645 |
NCBI Gene ID: | 2114 |
NCBI Accession: | P15036.1 |
UniProt Secondary Accession: | P15036,A1A4L6, |
UniProt Related Accession: | P15036 |
Molecular Weight: | 469 |
NCBI Full Name: | Protein C-ets-2 |
NCBI Synonym Full Names: | v-ets avian erythroblastosis virus E26 oncogene homolog 2 |
NCBI Official Symbol: | ETS2 |
NCBI Official Synonym Symbols: | ETS2IT1 |
NCBI Protein Information: | protein C-ets-2; oncogene ETS-2; v-ets erythroblastosis virus E26 oncogene homolog 2; v-ets avian erythroblastosis virus E2 oncogene homolog 2 |
UniProt Protein Name: | Protein C-ets-2 |
Protein Family: | Protein |
UniProt Gene Name: | ETS2 |
UniProt Entry Name: | ETS2_HUMAN |
Antibodies |
Anti-ETS2 Antibody (CAB14486) |
Anti-ETS2 Antibody (CAB16844) |
Anti-ETS2 Antibody (CAB16845) |
Anti-ETS2 Antibody (CAB7329) |
ETS2 Antibody (PACO09155) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |