ERAL1 Antibody, HRP conjugated (PACO48895)
- SKU:
- PACO48895
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ERAL1 Antibody, HRP conjugated (PACO48895) |
抗体コード: | PACO48895 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human GTPase Era, mitochondrial protein (271-382AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly. |
シノニム: | GTPase Era, mitochondrial (H-ERA) (hERA) (Conserved ERA-like GTPase) (CEGA) (ERA-W) (ERA-like protein 1), ERAL1, HERA |
UniProt Protein Function: | ERAL1: Probable GTPase that plays a role in the mitochondrial ribosomal small subunit assembly. Specifically binds the 12S mitochondrial rRNA (12S mt-rRNA) to a 33 nucleotide section delineating the 3' terminal stem-loop region. May act as a chaperone that protects the 12S mt-rRNA on the 28S mitoribosomal subunit during ribosomal small subunit assembly. Belongs to the Era/MnmE GTP-binding protein family. Era subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Mitochondrial Chromosomal Location of Human Ortholog: 17q11.2 Cellular Component: actin cytoskeleton; cytoplasm; intermediate filament cytoskeleton; mitochondrial matrix; mitochondrion Molecular Function:protein binding; ribosomal small subunit binding; rRNA binding Biological Process: ribosomal small subunit assembly and maintenance |
NCBI Summary: | The protein encoded by this gene is a GTPase that localizes to the mitochondrion. The encoded protein binds to the 3' terminal stem loop of 12S mitochondrial rRNA and is required for proper assembly of the 28S small mitochondrial ribosomal subunit. Deletion of this gene has been shown to cause mitochondrial dysfunction, growth retardation, and apoptosis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] |
UniProt Code: | O75616 |
NCBI GenInfo Identifier: | 57015286 |
NCBI Gene ID: | 26284 |
NCBI Accession: | O75616.2 |
UniProt Secondary Accession: | O75616,O75617, Q8WUY4, Q96LE2, Q96TC0, B3KN21, C9JEC6 |
UniProt Related Accession: | O75616 |
Molecular Weight: | 30,040 Da |
NCBI Full Name: | GTPase Era, mitochondrial |
NCBI Synonym Full Names: | Era like 12S mitochondrial rRNA chaperone 1 |
NCBI Official Symbol: | ERAL1 |
NCBI Official Synonym Symbols: | ERA; CEGA; ERA-W; H-ERA; ERAL1A; HERA-A; HERA-B |
NCBI Protein Information: | GTPase Era, mitochondrial |
UniProt Protein Name: | GTPase Era, mitochondrial |
UniProt Synonym Protein Names: | Conserved ERA-like GTPase; CEGA; ERA-W; ERA-like protein 1 |
UniProt Gene Name: | ERAL1 |
UniProt Entry Name: | ERAL1_HUMAN |