ENPP3 Antibody (PACO17828)
- SKU:
- PACO17828
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | ENPP3 Antibody (PACO17828) |
抗体コード: | PACO17828 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human ENPP3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO17828(ENPP3 Antibody) at dilution 1/80, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. |
シノニム: | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
UniProt Protein Function: | ENPP3: Cleaves a variety of phosphodiester and phosphosulfate bonds including deoxynucleotides, nucleotide sugars, and NAD. Belongs to the nucleotide pyrophosphatase/phosphodiesterase family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Nucleotide Metabolism - purine; EC 3.1.4.1; Cofactor and Vitamin Metabolism - riboflavin; Phosphodiesterase; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Motility/polarity/chemotaxis; Carbohydrate Metabolism - starch and sucrose; Cofactor and Vitamin Metabolism - pantothenate and CoA biosynthesis; EC 3.6.1.9 Chromosomal Location of Human Ortholog: 6q22 Cellular Component: integral to plasma membrane; perinuclear region of cytoplasm Molecular Function:phosphodiesterase I activity; nucleotide diphosphatase activity; nucleic acid binding; metal ion binding; nucleoside-triphosphate diphosphatase activity; scavenger receptor activity; polysaccharide binding Biological Process: receptor-mediated endocytosis; nucleoside triphosphate catabolic process; immune response; phosphate metabolic process; inorganic diphosphate transport |
NCBI Summary: | The protein encoded by this gene belongs to a series of ectoenzymes that are involved in hydrolysis of extracellular nucleotides. These ectoenzymes possess ATPase and ATP pyrophosphatase activities and are type II transmembrane proteins. Expression of the related rat mRNA has been found in a subset of immature glial cells and in the alimentary tract. The corresponding rat protein has been detected in the pancreas, small intestine, colon, and liver. The human mRNA is expressed in glioma cells, prostate, and uterus. Expression of the human protein has been detected in uterus, basophils, and mast cells. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14638 |
NCBI GenInfo Identifier: | 206729860 |
NCBI Gene ID: | 5169 |
NCBI Accession: | O14638.2 |
UniProt Secondary Accession: | O14638,Q5JTL3, |
UniProt Related Accession: | O14638 |
Molecular Weight: | 100,124 Da |
NCBI Full Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
NCBI Synonym Full Names: | ectonucleotide pyrophosphatase/phosphodiesterase 3 |
NCBI Official Symbol: | ENPP3 |
NCBI Official Synonym Symbols: | B10; NPP3; PDNP3; CD203c; PD-IBETA |
NCBI Protein Information: | ectonucleotide pyrophosphatase/phosphodiesterase family member 3; gp130RB13-6; phosphodiesterase-I beta; phosphodiesterase I/nucleotide pyrophosphatase 3; dJ914N13.3 (phosphodiesterase I/nucleotide pyrophosphatase 3); dJ1005H11.3 (phosphodiesterase I/nucleotide pyrophosphatase 3) |
UniProt Protein Name: | Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 |
UniProt Synonym Protein Names: | Phosphodiesterase I beta; PD-Ibeta; Phosphodiesterase I/nucleotide pyrophosphatase 3 |
UniProt Gene Name: | ENPP3 |
UniProt Entry Name: | ENPP3_HUMAN |