EMR2 Antibody (PACO04043)
- SKU:
- PACO04043
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | EMR2 Antibody |
抗体コード: | PACO04043 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | WB:1:500-1:2000, IF:1:200-1:1000 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human EMR2. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | EMR2; EGF-like module-containing mucin-like hormone receptor-like 2; EGF-like module receptor 2; CD antigen CD312 |
UniProt Protein Function: | EMR2: Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 2; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 19p13.1 Cellular Component: plasma membrane; integral to membrane Molecular Function:G-protein coupled receptor activity; calcium ion binding Biological Process: G-protein coupled receptor protein signaling pathway; cell migration; inflammatory response; cell adhesion |
NCBI Summary: | This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
UniProt Code: | Q9UHX3 |
NCBI GenInfo Identifier: | 108935835 |
NCBI Gene ID: | 30817 |
NCBI Accession: | Q9UHX3.2 |
UniProt Secondary Accession: | Q9UHX3,Q8NG96, Q9Y4B1, B4DQ96, E7ESD7, E9PBR1, E9PEL6 E9PFQ5, E9PG91, |
UniProt Related Accession: | Q9UHX3 |
Molecular Weight: | 90,472 Da |
NCBI Full Name: | EGF-like module-containing mucin-like hormone receptor-like 2 |
NCBI Synonym Full Names: | egf-like module containing, mucin-like, hormone receptor-like 2 |
NCBI Official Symbol: | EMR2 |
NCBI Official Synonym Symbols: | CD312 |
NCBI Protein Information: | EGF-like module-containing mucin-like hormone receptor-like 2 |
UniProt Protein Name: | EGF-like module-containing mucin-like hormone receptor-like 2 |
UniProt Synonym Protein Names: | EGF-like module receptor 2 |
UniProt Gene Name: | EMR2 |
UniProt Entry Name: | EMR2_HUMAN |